Pancreatic cancer is challenging to detect early because symptoms are often mild or vague. Knowing what to look for — and understanding your personal risk — can help lead to earlier diagnosis and better outcomes.
Common Symptoms
Digestive Changes:
- Persistent abdominal pain
- Indigestion or bloating
- Loss of appetite
Weight or Energy Changes:
- Unexplained weight loss
- Constant fatigue
Jaundice:
- Yellowing of skin or eyes
- Dark urine or pale stools
New Onset Diabetes
- Unexpected diabetes, especially without typical risk factors, may be a sign.
- If symptoms persist or progress, it’s important to speak with a healthcare provider.
Key Risk Factors
- Age: Most common after 50
- Family history: A close relative with pancreatic cancer increases risk
- Genetic mutations: BRCA1, BRCA2, PALB2, ATM, and others
- Chronic conditions: Long-term pancreatitis or long-standing diabetes
- Lifestyle factors: Smoking, obesity, and diets high in processed foods
Having risk factors doesn’t guarantee cancer — but it means screening may be especially important.
Why This Matters
Early detection leads to more treatment options and better survival. That’s why organizations like the PRECEDE Foundation are working to:
- Identify high-risk individuals
- Improve screening tools
- Make early detection more accessible
What You Can Do
- Know your family and medical history
- Pay attention to persistent symptoms
- Talk to a doctor if you have multiple risk factors
- Share information with others who may be at risk
Understanding symptoms and risk is a powerful first step toward earlier detection — and saving lives.