The Future Of Pancreatic Cancer Research: Trovanow’s Vision And Impact

June 13, 2023

Precede Foundation

The pancreas plays an incredibly important role in overall health, aiding with digestion and regulation of the amount of sugar in your bloodstream. Unfortunately, cancer is the second leading cause of death among men and women in the United States. Within that, pancreatic cancer is the third-leading cause of cancer deaths and the number of people diagnosed with it is on the rise every year.

Pancreatic cancer remains one of the most challenging and devastating diseases, with low survival rates and limited treatment options. Pancreatic cancer rarely causes symptoms until it’s quite advanced, so most people have widespread disease at the time they’re diagnosed. The pancreas is deep inside the middle of the body, so early tumors can’t be seen or felt by healthcare providers during routine physical exams.

Sadly, pancreatic cancer still has one of the lowest 5-year survival rates of any kind of cancer, at about 12%. It’s time to dramatically improve that number. Every day, more than 1,257 people WORLDWIDE are diagnosed with pancreatic cancer. An unacceptably high proportion of these cases are diagnosed at stage 3 or 4. Early detection is the key to improving patient outcomes.

TrovaNow is an organization that raises funds to support the Pancreatic Cancer Early Detection (PRECEDE) Consortium. PRECEDE’s mission is to transform the outcome and survival rates of pancreatic cancer through early detection. Our goal is to increase the 5-year survival rate from 12% to 50% within the next 10 years. Here’s what you need to know!

The Importance of Early Detection and Prevention: Investing in early detection is essential in battling pancreatic cancer. Detecting the disease in its beginning stages greatly increases the likelihood of timely treatment and better patient outcomes.

TrovaNow understands the importance of early detection and prevention and utilizes its resources to support research programs that target early identification. The ultimate goal of TrovaNow’s efforts is to reduce the impact of pancreatic cancer on patients and improve their overall quality of life.

TrovaNow: Advancing Early Detection Research: TrovaNow has positioned itself at the forefront of the battle against pancreatic cancer through its unwavering commitment to early detection through its support of the PRECEDE Consortium. PRECEDE is a groundbreaking research collaboration focused on improving early detection methods for pancreatic cancer.

TrovaNow supports the exploration and development of cutting-edge technologies, advanced imaging techniques, and novel biomarkers and liquid biopsies to identify pancreatic cancer at its earliest and most treatable stages. By investing in these innovative approaches, TrovaNow is driving the progress of early detection research and paving the way for improved patient outcomes.

Collaborations and Partnerships: To accelerate advancements in early detection research, TrovaNow has formed strategic partnerships with leading research institutions and garnered support from medical professionals and experts in the field. By fostering collaborations, TrovaNow enables the exchange of knowledge, resources, and expertise, creating synergistic efforts.

These partnerships empower researchers to pool their strengths, leverage state-of-the-art technologies, and conduct large-scale studies to make significant strides in identifying pancreatic cancer earlier. Through these collaborations, TrovaNow amplifies the impact of research efforts and fosters an environment of collective expertise focused on the early detection of pancreatic cancer.

TrovaNow’s Vision: Increasing 5-Year Survival Rates: TrovaNow’s ultimate goal is to increase the 5-year survival rate for pancreatic cancer from the current 12% to an ambitious 50% within the next 10 years. This vision drives their dedication to funding early detection research. By detecting the disease at an earlier stage, patients can receive timely interventions, leading to improved treatment options and increased survival rates.

TrovaNow’s commitment to this vision instills hope for a future where pancreatic cancer is no longer a devastating diagnosis. By investing in research initiatives focused on early detection, TrovaNow is paving the way for significant improvements in patient outcomes and transforming the landscape of pancreatic cancer.

Success Stories and Promising Results: TrovaNow’s support has already yielded promising results. Through collaborative research efforts, they have witnessed success stories of early detection leading to improved patient outcomes. Innovative screening tools, advanced imaging techniques, and the exploration of biomarkers have all contributed to identifying pancreatic cancer in its early stages, increasing the chances of successful treatment. These success stories provide inspiration and hope for both patients and medical professionals.

Patient testimonials serve as a testament to the positive impact TrovaNow’s research support has made in their lives, underscoring the significance of early detection in improving prognosis and survival rates for pancreatic cancer.

Challenges and Future Directions: While TrovaNow has made significant strides in advancing early detection research, challenges remain. Pancreatic cancer’s elusive nature and lack of easily detectable symptoms pose hurdles in identifying the disease at its earliest stages. However, TrovaNow remains steadfast in its commitment to overcoming these challenges. They aim to expand research efforts, foster additional collaborations, and explore emerging technologies to refine early detection methods. By addressing these challenges head-on, TrovaNow aims to further enhance the accuracy and effectiveness of early detection strategies for pancreatic cancer. Continued support and funding are crucial to sustaining these research initiatives and paving the way for further breakthroughs.

TrovaNow’s vision and impact on pancreatic cancer research, specifically in the realm of early detection, cannot be overstated. By raising funds and supporting collaborative research efforts, TrovaNow is pushing the boundaries of knowledge and innovation in the field. With a goal of increasing the 5-year survival rate for pancreatic cancer, TrovaNow is leading the charge toward earlier detection, better treatment options, and improved patient outcomes. Through their unwavering commitment, we can look forward to a future where pancreatic cancer is diagnosed early, enabling more lives to be saved.

Every year, National Cancer Survivor Month is celebrated in June. This month recognizes and celebrates the millions of people who have bravely and successfully battled cancer.

We encourage you to check in, offer support and share resources to those coping with life as a cancer survivor.

Giving is not just about making a donation, it’s about making a difference. Join us in our mission and donate today to advance the early detection of pancreatic cancer and save lives. Visit www.trovanow.com to learn how you can get involved and donate today.

Knowing When To Ask For Help

There’s strength in recognizing when you need additional support. If you’re feeling consistently overwhelmed, anxious, or depressed, it may be time to speak with a healthcare professional. Warning signs can include ongoing sleep trouble, loss of appetite, or emotional numbness.

Mental health care is an important part of cancer recovery. There are therapists, social workers, and cancer-specific counselors trained to support your unique needs. Don’t hesitate to seek them out.

Your medical team can help adjust medications or recommend physical therapy if your symptoms are impacting your daily life. Being honest about your struggles allows your care providers to offer better, more personalized support.

The path to recovery from pancreatic cancer is rarely straightforward. It’s a mix of triumphs and setbacks, strength and vulnerability. But through each high and low, healing is happening. Be gentle with yourself. Allow space for rest, reflection, and growth.

You don’t have to go through this journey alone. With the right support, emotional, physical, and practical, you can move forward, one step at a time. And remember, every day you show up for yourself is a victory.

At TrovaNOW, we’re focused on finding a cure for pancreatic cancer. Every test and discovery brings us closer to better treatments and saving lives. Join us and learn more at TrovaNOW.

How To Navigate The Ups and Downs of Cancer Recovery

Recovering from pancreatic cancer is a journey filled with emotional highs, physical lows, and everything in between. It’s a deeply personal process that often doesn’t follow a straight path. There are days of hope and improvement, and days when fatigue, fear, or frustration take over. While every patient’s experience is unique, certain strategies can help you cope more effectively with the ups and downs of recovery. This guide offers support and practical advice for patients and caregivers as they move through the challenging journey of healing.

Understanding the Recovery Journey

Recovery doesn’t look the same for everyone. For many pancreatic cancer survivors, healing after treatment involves more than just physical recovery, it’s about rebuilding your energy, mental well-being, and confidence. After surgery or chemotherapy, the body may feel weak, digestion may be affected, and simple tasks can feel overwhelming. It’s important to remember that this phase is temporary. While the progress may be slow, every step forward matters.

Setbacks can be discouraging, but they’re also normal. It’s okay to feel frustrated or afraid. Rather than expecting a perfect recovery, give yourself permission to heal at your own pace. Track your progress by reflecting on how far you’ve come rather than how far you still have to go.

Managing Physical Side Effects

Your body needs time to recover after treatment. Nutrition and hydration are key to restoring your strength. Eating small, nutrient-rich meals throughout the day can help support your digestive system, which may be more sensitive post-treatment. If you’re struggling with nutrient absorption, your care team may recommend digestive enzymes to help your body process food more effectively.

Incorporating light movement into your daily routine, such as short walks or gentle stretching, can improve circulation and boost energy. It’s important to find a balance between resting and staying active, as gentle movement supports both your physical and mental well-being.

Hydration is equally important. Water aids in healing and helps manage symptoms like fatigue and nausea. Keep a water bottle nearby and sip regularly throughout the day to stay hydrated, which can also reduce nausea. If digestion is an issue, your doctor may suggest digestive enzymes to help your body absorb nutrients more effectively.

Regular check-ups with your doctor are crucial to monitor your recovery progress and adjust treatments as needed to ensure the best outcomes.

Navigating Emotional Ups and Downs

Emotional recovery often takes longer than physical healing. After treatment ends, many survivors feel a mix of relief, anxiety, sadness, and uncertainty. It’s completely normal to feel afraid of recurrence or to grieve the life you had before cancer.

You might also feel isolated or misunderstood. That’s why emotional support is essential. Talking to a therapist, counselor, or support group can make a significant difference. You don’t have to carry the weight of recovery alone.

Journaling is another helpful tool. Writing down your thoughts allows you to process emotions and track patterns in your recovery. Mindfulness practices like meditation or breathing exercises can help ground you during anxious moments. Even on difficult days, remember that emotional healing is part of the recovery, not a separate journey.

Staying Connected to Support

Your support network is an important part of your recovery. Whether it’s family, friends, or caregivers, the people around you can offer emotional reassurance and practical help. Let them, it’s okay to ask for assistance or to admit when you’re having a tough day.

Support groups, whether in-person or virtual, can provide a powerful sense of community. Connecting with other survivors who understand what you’re going through can bring comfort, hope, and valuable insights. Caregivers should also seek support, as they too face emotional and physical challenges.

Open communication is key. Let your loved ones know how they can help, and express your needs clearly. Sometimes, just having someone sit with you or listen can make a huge difference.

Finding Purpose and Routine Again

As your body heals, it’s natural to want to regain a sense of control and purpose. Rebuilding routines can help you feel more grounded and optimistic. Start small. Set simple goals, like making your bed, taking a walk, or preparing a meal. These acts of daily living are powerful milestones in recovery.

Hobbies, creative outlets, and even new interests can provide positive distractions and a renewed sense of identity. You may not be able to do everything you once could, but you can find new ways to experience joy and fulfillment.

Re-establishing structure in your day, such as regular wake-up times or planned activities, can restore confidence and give you something to look forward to. Routine doesn’t just support physical recovery, it also significantly impacts emotional well-being.

Tracking Progress Without Pressure

It’s easy to feel overwhelmed by the slow pace of recovery. That’s why it’s important to measure progress in realistic, compassionate ways. Instead of focusing only on what hasn’t improved, keep track of what has.

Consider using a journal or app to record symptoms, energy levels, and small victories. You might notice that you’re sleeping better, walking farther, or eating more consistently than a few weeks ago. Celebrate these moments.

Be mindful not to compare your journey with others. Every recovery is unique. If you have a bad day or experience a setback, that doesn’t erase your progress. Growth includes rest, and healing is not a linear path.

Knowing When to Ask for Help

At TrovaNOW, we’re focused on finding a cure for pancreatic cancer. Every test and discovery brings us closer to better treatments and saving lives. Join us and learn more at TrovaNOW.

Foods That May Promote A Healthier Pancreas

The pancreas is a small yet vital organ that performs essential functions in digestion and blood sugar regulation. It produces digestive enzymes to break down food and hormones like insulin to control blood sugar. However, when this organ becomes damaged or inflamed, it can lead to serious health conditions, including pancreatitis, diabetes, and even pancreatic cancer. Although a healthy diet alone can’t prevent or cure pancreatic cancer, certain foods may help protect the pancreas, reduce inflammation, and support overall wellness. This blog explores how dietary choices may contribute to pancreatic health, particularly in relation to the risk of pancreatic cancer.

Why Pancreatic Health Matters

The pancreas is responsible for two essential functions: producing enzymes that break down food and secreting insulin to regulate blood sugar. When the pancreas is functioning properly, it efficiently supports digestion and metabolic balance.

However, pancreatic cancer is particularly dangerous because it is often diagnosed late, after the cancer has spread. The exact cause of pancreatic cancer is not always clear, but lifestyle factors, including diet, can contribute to either increasing or reducing the risk. Chronic inflammation, oxidative stress, and insulin resistance are believed to contribute to the development of pancreatic cancer. Eating nutrient-dense foods that help reduce these factors may help reduce your risk and support the healing process if cancer is present.

Foods That Support Pancreatic Health and May Help Reduce the Risk of Pancreatic Cancer

Antioxidant-Rich Fruits and Vegetables

Fruits and vegetables are rich in antioxidants, which neutralize harmful free radicals and reduce oxidative stress, both of which are associated with pancreatic damage and cancer development. Antioxidants also support the body’s immune system, making it better equipped to fight off abnormal cell growth. Best choices include:

Blueberries
Cherries
Spinach
Kale
Red cabbage

These foods are packed with vitamins A, C, and E, which protect cells from oxidative damage. They also contain phytonutrients that have anti-inflammatory properties, crucial in reducing cancer risk. Consuming a variety of colorful produce helps provide a broad range of nutrients that support overall health and well-being.

Whole Grains

Whole grains are rich in fiber, which helps stabilize blood sugar levels and reduce strain on the pancreas. Refined carbohydrates, like white bread and sugary foods, can cause insulin spikes, which put stress on the pancreas and may contribute to cancer risk. Pancreas-friendly whole grains include:

Brown rice
Quinoa
Oats
Barley

Incorporating whole grains into your diet can help maintain blood sugar levels and prevent insulin resistance, a key factor in the development of pancreatic cancer. The fiber in whole grains also promotes healthy digestion, reducing inflammation and protecting the pancreas.

Healthy Fats in Moderation

While unhealthy fats can stress the pancreas, certain healthy fats provide anti-inflammatory benefits and support overall pancreatic health. Inflammation is a significant factor in pancreatic cancer, so consuming moderate amounts of healthy fats can help reduce this risk. Good sources of healthy fats include:

Avocados
Olive oil
Nuts (like almonds and walnuts)
Seeds (like flax and chia)

These unsaturated fats support immune function and nutrient absorption. However, it’s important to consume these fats in moderation, as excessive fat intake can overwhelm the pancreas, especially for individuals with pancreatic cancer or pancreatitis.

Lean Proteins

Protein is essential for repairing tissues and maintaining muscle mass, especially for those undergoing cancer treatment. However, fatty cuts of meat can exacerbate inflammation and increase cancer risk, so choosing lean proteins is a healthier option. Healthy protein options include:

Skinless poultry
White fish (like cod or tilapia)
Tofu
Legumes (like lentils and chickpeas)

Opting for lean, plant-based proteins can provide essential amino acids while avoiding the inflammatory effects of red meats and processed meats. Grilling, steaming, or baking these proteins is a healthier cooking method than frying.

Probiotic and Fermented Foods

Gut health is closely linked to pancreatic health. A healthy gut microbiome supports immune function and may help prevent chronic inflammation, which is a key player in the development of pancreatic cancer. Probiotic-rich foods can also enhance digestion and strengthen the body’s ability to absorb nutrients. Helpful fermented foods include:

Plain yogurt with live cultures
Kefir
Sauerkraut
Kimchi
Miso

These fermented foods provide beneficial bacteria that balance the gut microbiome, helping reduce systemic inflammation and promoting overall health. Be mindful to choose versions without added sugars or high sodium content, which could counteract the benefits.

Hydration and Herbal Support

Staying hydrated is essential for maintaining the proper function of the pancreas, especially when dealing with conditions like pancreatic cancer. Water supports digestion, nutrient transport, and the production of digestive enzymes, all of which are important for pancreatic health. Tips for hydration and herbal support:

Drink at least 8 cups of water daily.
Herbal teas like ginger, chamomile, and turmeric have anti-inflammatory properties and may help alleviate some symptoms of pancreatic inflammation.
Avoid sugary drinks, alcohol, and excessive caffeine, which can irritate the pancreas and exacerbate inflammation.

Herbal teas, such as ginger and turmeric, have been studied for their potential to reduce inflammation and may offer benefits to those dealing with pancreatic cancer.

Foods to Limit or Avoid for Pancreatic Health

Certain foods are known to increase the risk of pancreatic cancer and should be limited or avoided to protect the pancreas. Foods to avoid or limit include:

Fried and greasy foods: These are high in unhealthy fats that are difficult for the pancreas to process and can worsen inflammation.
Processed meats: Bacon, sausage, and deli meats are linked to higher rates of pancreatic cancer due to their high levels of nitrates and saturated fats.
Sugary foods and refined carbs: Candy, soda, white bread, and pastries can cause blood sugar spikes, promoting insulin resistance and inflammation.
Alcohol: Excessive alcohol consumption is a major risk factor for both pancreatitis and pancreatic cancer.

Limiting these foods can help reduce the load on your pancreas and lower the risk of developing pancreatic cancer or other pancreatic diseases.

Lifestyle Tips to Complement a Pancreas-Friendly Diet

In addition to dietary changes, certain lifestyle habits can significantly support pancreatic health, especially for those concerned about pancreatic cancer. Helpful lifestyle tips include:

Eat smaller, more frequent meals: This reduces the digestive workload and is gentler on the pancreas.
Exercise regularly: Physical activity helps regulate blood sugar and supports healthy weight management, both of which are important in reducing cancer risk.
Quit smoking: Smoking is a known risk factor for pancreatic cancer, and quitting can dramatically lower your chances of developing the disease.
Get regular checkups: Especially if you have a family history of pancreatic cancer or other risk factors, routine health screenings are essential for early detection.
Manage stress: Chronic stress can impact the body’s immune function and digestion. Practices like yoga, meditation, or simple relaxation techniques can help support pancreatic health.

Supporting pancreatic health through a diet rich in whole grains, lean proteins, healthy fats, and antioxidant-rich fruits and vegetables may not only promote a healthier pancreas but also lower the risk of pancreatic cancer. While no food can prevent or cure cancer, the foods you choose can significantly impact your body’s ability to fight inflammation, manage blood sugar, and maintain overall health. Always consult with a healthcare provider before making significant changes to your diet, especially if you are managing a pancreatic condition.

By adopting a pancreas-friendly diet and lifestyle, you are taking proactive steps toward improving your long-term health and reducing the risk of pancreatic cancer.

How TrovaNow Can Support Your Health Journey

At TrovaNow, we understand the importance of taking care of your health, especially when facing serious conditions like pancreatic cancer. Our platform offers helpful resources, advice, and support to guide you in making informed health decisions.

We also support pancreatic cancer research and awareness initiatives. By donating or learning more about these efforts, you can help improve outcomes for those affected by the disease. Visit TrovaNow to learn more and get involved.

Is There A Connection Between Gut Health & Pancreatic Cancer?

For good reason, gut health has become a hot topic in the world of wellness. The trillions of microorganisms living in our digestive tract, known as the gut microbiome, are crucial to the functioning of our bodies. From digestion and nutrient absorption to mood regulation and immune defense, a healthy gut supports nearly every system in the body. But can it also influence something as serious as pancreatic cancer?

Pancreatic cancer is one of the most aggressive and challenging cancers to detect and treat. With rising awareness around the importance of gut health, researchers are now asking an important question ‘Is there a connection between gut health and pancreatic cancer?’ In this blog, let’s explore what it might mean for prevention or treatment and how maintaining a balanced gut could support overall wellness.

What Does Gut Health Actually Mean?

When people talk about gut health, they’re usually referring to the balance and function of the digestive system, including the bacteria that live in the intestines. This complex ecosystem, known as the gut microbiome, includes a mix of good and bad bacteria, fungi, and other microbes.

A healthy gut means:

Proper digestion and nutrient absorption.
A strong intestinal barrier.
Balanced immune activity.
Low levels of chronic inflammation.

Several lifestyle choices help support gut health:

Eating a high-fiber diet rich in fruits, vegetables, legumes, and whole grains.
Consuming fermented foods like yogurt, kimchi, and kefir.
Staying hydrated.
Limiting processed foods, sugar, and alcohol.
Getting enough sleep and managing stress.

These habits help promote a thriving and healthy microbiome, which in turn supports better physical and mental health.

Understanding Pancreatic Cancer

Pancreatic cancer begins in the tissues of the pancreas, a gland located behind the stomach that helps regulate blood sugar and digestion by producing insulin and enzymes. There are different types, but pancreatic ductal adenocarcinoma is the most common and deadly.

One of the biggest challenges with pancreatic cancer is that it’s often diagnosed late, after it has already spread to other organs. Early symptoms like fatigue, digestive discomfort, or mild weight loss are often overlooked.

Even though not all causes are fully understood, lifestyle and inflammation appear to affect how this cancer develops.

Risk factors include:

Smoking
Obesity
Type 2 diabetes
Chronic pancreatitis
A family history of pancreatic cancer
Certain genetic mutations (e.g., BRCA2)

How Are the Gut and Pancreas Connected?

The gut and pancreas work closely together. The pancreas produces enzymes that help break down fats, proteins, and carbohydrates in the small intestine. It also releases hormones like insulin to regulate blood sugar.

The gut microbiome may influence the pancreas in more ways than digestion alone. Research has shown that dysbiosis, an imbalance in gut bacteria, can trigger chronic inflammation and disrupt the immune system. Over time, this may contribute to cellular damage and disease in nearby organs, including the pancreas.

There’s growing interest in how gut microbes:

Interact with the immune system.
Affect inflammation in and around the pancreas.
Influence the environment in which tumors grow (known as the tumor microenvironment).

These interactions suggest a potential link between gut health and pancreatic cancer development.

What Does the Research Say?

While the science is still evolving, early research has found some fascinating findings.

1 – Microbiome Differences in Pancreatic Cancer Patients

Studies have found that the gut microbiomes of people with pancreatic cancer often look different from those without the disease. Certain harmful bacteria may be more abundant, while beneficial bacteria may be lacking. Researchers are investigating whether these changes contribute to cancer development or if the cancer itself causes changes in the microbiome.

2 – Bacterial Signatures Linked to Tumor Behavior

Specific bacterial strains in the gut or even inside pancreatic tumors may affect how the tumor grows and spreads. Some bacteria may fuel inflammation, suppress the body’s ability to detect and destroy cancer cells, or make the tumor more resistant to treatments like chemotherapy.

3 – Microbiome and Treatment Response

There’s also growing interest in how the gut microbiome may change cancer treatment effectiveness. In other cancers, gut bacteria have been shown to influence how well patients respond to immunotherapy, a treatment that uses the body’s immune system to fight cancer. While research in pancreatic cancer is still early, similar patterns are being explored.

Can Supporting Gut Health Help?

While gut health alone can’t prevent or cure pancreatic cancer, maintaining a healthy microbiome may offer supportive benefits, especially for patients in treatment or recovery.

Here’s how:

Improved digestion and nutrient absorption during or after treatment.
Reduced inflammation, which may help support the immune system.
Better tolerance of certain cancer treatments.
Enhanced overall well-being, including energy, mood, and sleep.

Many doctors now recommend gut-friendly lifestyle changes for cancer patients and survivors. These include:

Eating more whole plant-based foods.
Including fermented foods like sauerkraut, kombucha, and plain yogurt.
Staying physically active.
Avoid processed foods and added sugars.
Using probiotics (if advised by a doctor).

Again, these habits are not a substitute for treatment, but they may help the body better cope with the challenges of cancer and recovery.

What We Still Don’t Know

While the link between gut health and pancreatic cancer is promising, there’s still a lot we don’t understand.

It’s not clear whether microbiome changes cause pancreatic cancer or happen because of it.
Most of the research so far is in animals or small human studies.
More clinical trials are needed to test whether changing gut bacteria can directly improve patient outcomes.
There’s no single probiotic or diet proven to prevent pancreatic cancer. That’s why it’s important to avoid unproven treatments or extreme dietary changes without medical guidance.

Gut health is more than just digestion, it’s a central part of overall wellness. As scientists continue to explore the gut-pancreas connection, early findings suggest that the microbiome may help in the development and progression of pancreatic cancer.

While we don’t have all the answers yet, taking care of your gut is still a smart and practical choice. A balanced gut may help reduce inflammation, support the immune system, and improve quality of life, especially for those facing or recovering from serious illnesses.

If you’re concerned about your gut health or cancer risk, talk to your healthcare provider. They can help you find safe and evidence-based ways to support your body, inside and out.

At TrovaNow, we’re committed to supporting research, education, and innovation in the fight against pancreatic cancer. Join us in our mission to advance the early detection of pancreatic cancer, change the future of this disease, and improve survival rates. Together, we can help create a future where pancreatic cancer is detected earlier, treated more effectively, and more lives are saved.