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Precede Foundation Tribute Posts

In Loving Memory of Jeff Johnson

In March 2020, I was diagnosed with pancreatic cancer, but I was fortunate enough to make it through both chemo and the Whipple surgery successfully. Much of that success had to do with brilliant doctors that treated me, but also on the fact that my cancer was discovered in its early stages. I have been cancer free since July 2020.

After the completion of my treatment, my surgeon, Diane Simeone, told me about the PRECEDE Consortium and its fundraising arm, TrovaNow, and how these organizations were dedicated to finding a test for early detection of this insidious disease. The five year survival rate for pancreatic cancer was only 10%, and the goal was to increase the survival rate to 50% within the next ten years. I decided to get involved, and my firm, Pryor Cashman, graciously agreed that we would provide legal services to PRECEDE and TrovaNow on a pro bono basis. When that decision was first made, many of my partners and colleagues pitched in, but the person who stepped up the most was my longtime friend and law partner, Jeffrey Johnson.

When Jeff first got involved with PRECEDE and TrovaNow, there were many contractual and IP issues that needed attention. We also needed to complete deals with companies that needed access to PRECEDE patient samples so that they could test their own early detection tests. Jeff got involved early and often in all of this work, graciously devoting his time and attention to this very worthy cause. In the process, he became a crucial member of the TrovaNow Board of Directors.

Then, in what can only be described as an incredibly unfortunate coincidence, as he was devoting more and more time to the PRECEDE/TrovaNow cause, Jeff was also diagnosed with pancreatic cancer. It was relatively early, but not as early in the process as mine, so his chemo treatment and his Whipple were more complicated.

And despite having to deal with his own medical issues, Jeff continued to devote a significant amount of his time to all of the legal issues that still needed resolution, including helping to strengthen the bridge between the doctors that led the Consortium and the volunteers who gave their time to TrovaNow. Everyone loved working with Jeff, not only because he was smart, insightful and creative, but also because he was always upbeat and positive, just an absolute pleasure to be with.

A few months ago, Jeff’s health took a turn for the worse and he needed to undergo more chemo treatments and a number of sessions of radiation. Despite
this, Jeff never stopped helping other people, devoting whatever time and energy he could to help the cause. Unfortunately, in June 2024, Jeff experienced some additional and serious health setbacks. On July 7, 2024, he succumbed to this disease and died peacefully at home, surrounded by his loving family. He was only 65.

As we ramp up our fundraising effort for PRECEDE and TrovaNow in the weeks and months ahead, we wish to pay tribute to our dear friend and esteemed colleague, Jeffrey Johnson. And as we mourn his passing, we think about the importance of early testing and how it could have made a difference in his life.

Please give as much as you can to support our organization. Please do it in Jeff’s honor or in honor of any other friend or loved one who faces this horrible disease.

Thank you.
Jamie M. Brickell
President, TrovaNow

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The Power Of Genetic Testing In Pancreatic Cancer Screening

Pancreatic cancer remains one of the most challenging cancers to detect and treat effectively. Often diagnosed at advanced stages, the prognosis for pancreatic cancer patients is typically poor, with a five-year survival rate of around 13%. However, advancements in medical technology, particularly in genetic testing, are offering new hope for early detection and personalized treatment strategies.

This blog post aims to educate readers on the significance of genetic testing in pancreatic cancer screening, emphasizing its potential to transform early detection and personalized treatment approaches in the field of oncology.

Genetic Basis of Pancreatic Cancer

Pancreatic cancer arises when cells in the pancreas, a vital organ located behind the stomach, begin to grow uncontrollably. There are several types of pancreatic cancer, the most common being pancreatic adenocarcinoma. Symptoms often do not manifest until the cancer has progressed significantly, making treatment particularly difficult.

Research has shown that genetic mutations may play a significant role in the development of pancreatic cancer. Certain inherited genetic mutations, such as those in the BRCA1, BRCA2, and PALB2 genes, increase an individual’s risk of developing pancreatic cancer. These mutations are also associated with other cancers, such as breast and ovarian cancer, highlighting the interconnectedness of genetic factors in cancer development.

Role of Genetic Testing in Pancreatic Cancer Screening

Genetic testing involves analyzing a person’s DNA to identify specific genetic mutations that may predispose them to pancreatic cancer. This testing can be performed on germline DNA, which is inherited from both parents or on somatic DNA, which refers to genetic mutations that occur during a person’s lifetime in specific cells.

The primary goal of genetic testing in pancreatic cancer screening is early detection and risk assessment. Individuals with a family history of pancreatic cancer or known genetic mutations associated with the disease can benefit greatly from genetic testing. By identifying high-risk individuals early, healthcare providers can implement personalized screening programs and surveillance strategies to detect pancreatic cancer at its earliest and most treatable stages.

Advantages of Early Detection Through Genetic Testing

Early detection of pancreatic cancer through genetic testing offers several advantages. Firstly, it allows for timely intervention and treatment, potentially improving outcomes and survival rates. Secondly, it enables healthcare providers to customize screening and surveillance strategies based on an individual’s genetic risk profile, optimizing resources and improving the efficiency of healthcare delivery.

Case studies and research have demonstrated the effectiveness of genetic testing in identifying individuals at high risk for pancreatic cancer. For example, individuals carrying BRCA mutations have been found to have a significantly increased risk of developing pancreatic cancer compared to the general population. By identifying these mutations early, healthcare providers can offer these individuals personalized screening plans, which may include more frequent imaging tests or preventive measures.

Challenges and Considerations

Despite its promise, genetic testing in pancreatic cancer screening faces several challenges. Ethical considerations, such as patient privacy and informed consent, must be carefully addressed to ensure individuals fully understand the implications of genetic testing results.

The cost of genetic testing and accessibility to testing facilities remain significant barriers for many individuals, especially in underserved communities. Genetic testing can be expensive, and not all insurance plans cover the full cost, which can deter individuals from undergoing testing, particularly those without adequate financial resources or insurance coverage. Additionally, the availability of genetic testing facilities may be limited in rural or remote areas, further hindering access for individuals in these regions. This geographical difference can make healthcare access and outcomes worse for some pancreatic cancer patients.

Public health campaigns and educational programs aim to raise awareness about the importance of genetic testing and advocate for equitable access to testing services for all individuals at risk of pancreatic cancer.

It’s important to note that genetic testing may not provide definitive answers for everyone. False positives and false negatives can occur, potentially causing unnecessary anxiety or leading to missed opportunities for early intervention. Therefore, the interpretation of genetic testing results requires expertise and careful consideration of individual and familial risk factors to guide appropriate medical decisions.

The Future of Genetic Testing in Pancreatic Cancer

Advancements in genetic testing technology and research hold promise for the future of pancreatic cancer screening. Researchers continuously identify new genetic mutations associated with pancreatic cancer risk, expanding the application of genetic testing beyond known high-risk genes. This ongoing research enhances the potential benefits of genetic testing by offering more comprehensive risk assessments.

Innovations in genomic sequencing and bioinformatics are crucial. These advancements not only improve the accuracy and efficiency of genetic testing but also make it increasingly accessible and cost-effective over time. This progress is essential to integrate genetic testing into routine pancreatic cancer screening protocols, potentially leading to earlier detection and improved patient outcomes.

Personalized medicine, where treatments match a person’s genetic profile, is gaining importance in cancer care. Genetic testing in pancreatic cancer is key for developing personalized treatments. By understanding a patient’s genetic makeup, doctors can select treatments that may be more effective, reducing side effects and enhancing quality of life.

Looking ahead, investing in research and technology is critical to refine genetic testing and expand its benefits in pancreatic cancer care. By leveraging genetic insights, we aim to enhance early detection and personalized treatment options, which could significantly enhance outcomes for pancreatic cancer patients.

Join TrovaNow in Advancing Early Detection of Pancreatic Cancer

Genetic testing represents a powerful tool in the fight against pancreatic cancer, offering potential for early detection, personalized treatment plans, and improved survival rates. While challenges remain, ongoing research and technological advancements are crucial for a future where genetic testing becomes increasingly important in cancer prevention and management.

At TrovaNow, we are dedicated to advancing early detection of pancreatic cancer to save lives. As we learn more about the genetic factors influencing pancreatic cancer, it is crucial for those at high risk to consider genetic testing and personalized screening options. By using genetic information, we believe we can significantly reduce the impact of pancreatic cancer and improve patient outcomes.

Join us in our mission to make a difference. Your support can help fund vital research and initiatives aimed at early detection strategies. Get involved today; every contribution counts. Together, we can create a future where pancreatic cancer is detected early and treated effectively.

 

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Tips For Pancreatic Cancer Patients To Stay Healthy And Active

Pancreatic cancer is a challenging diagnosis, impacting patients’ health and overall wellbeing. It brings physical and emotional hurdles that can make everyday activities difficult. Despite these challenges, maintaining health and staying active are crucial for improving quality of life and managing symptoms. Engaging in healthy habits can help boost energy levels, enhance mood, and support the body during treatment. This blog provides thorough tips to help pancreatic cancer patients navigate their journey with practical advice on nutrition, physical activity, and overall well-being, enabling them to take an active role in their health and recovery.

Nutritional Tips for Pancreatic Cancer Patients

Pancreatic cancer begins in the tissues of the pancreas, a vital organ for digestion and blood sugar regulation. Common symptoms include jaundice, weight loss, abdominal pain, and digestive issues. Diagnosing pancreatic cancer typically involves imaging tests, blood tests, and biopsies. Treatment options vary depending on the stage of the disease but often include surgery, chemotherapy, radiation therapy, and targeted therapies. Understanding these basics equips patients and caregivers to make thoughtful decisions about health and lifestyle adjustments. Maintaining a balanced diet is essential for pancreatic cancer patients, as it supports overall health and helps manage treatment side effects. Consider these essential nutritional tips:

  • Balanced Diet Importance

Proper nutrition provides the necessary nutrients to maintain energy levels, support the immune system, and promote healing – helping the body repair and recover. Additionally, a well-planned diet can alleviate some of the digestive issues and nutritional deficiencies that may arise during treatment. Eating lots of fruits, vegetables, lean proteins, and whole grains is good for you.

  • Foods to Avoid

Certain foods can be difficult to digest and exacerbate symptoms. It’s essential to be mindful of fatty foods such as fried foods, high-fat meats, and creamy sauces, which can be hard to digest and may cause discomfort. Sugary foods like sweets and sugary drinks can lead to blood sugar spikes, potentially worsening fatigue and nausea. Spicy and acidic foods can irritate the digestive tract and increase discomfort, particularly for those experiencing gastrointestinal issues.

  • Hydration

Staying hydrated is crucial, especially if experiencing diarrhea or vomiting due to pancreatic cancer or its treatments. Adequate hydration helps maintain fluid balance, supports digestion, and promotes overall well-being. Water, herbal teas, and clear broths are excellent choices to stay hydrated. Additionally, electrolyte drinks can help replenish lost minerals and maintain electrolyte balance, which is essential for preventing dehydration and supporting recovery.

Physical Activity Recommendations

Regular physical activity offers numerous benefits, including improved mood, increased energy levels, and better overall health. Exercise can help reduce fatigue, enhance physical function, and improve mental health. It can also support the body’s ability to handle treatments better. 

  • Types of Suitable Exercises

Walking is a simple and flexible activity that can be adjusted to any fitness level, while swimming, gentle on the joints and muscles, serves as an excellent low-impact exercise; yoga focuses on gentle stretching and mindfulness, promoting relaxation and flexibility, and stretching keeps muscles limber and helps prevent stiffness.

  • Creating a Routine

Developing a consistent exercise routine can be beneficial. Begin with small, achievable goals and slowly increase your activity level over time. Aim for at least 2-3 hours of moderate-intensity exercise per week, but listen to your body and adjust as needed.

  • Listening to Your Body

Listening to your body’s signals is crucial in managing pancreatic cancer. It’s important to pay attention to cues of fatigue or pain and prioritize rest when needed. Avoid pushing through severe discomfort, as this can exacerbate symptoms and hinder recovery. Balancing activity with adequate rest and recovery time is essential for maintaining energy levels and overall well-being during treatment. Taking breaks when necessary allows the body to recuperate and supports a more sustainable approach to physical activity.

Managing Side Effects and Symptoms

Pancreatic cancer treatment often comes with challenging side effects. Patients may experience fatigue, nausea, pain, digestive issues, and loss of appetite. Here are practical strategies to manage them:

  • Coping Strategies

Coping strategies for managing pancreatic cancer include eating smaller, frequent meals to manage nausea and maintain energy levels, practicing relaxation techniques such as deep-breathing exercises, meditation, and gentle massages to alleviate pain and reduce stress, and ensuring hydration and electrolyte balance to manage fatigue and digestive issues.

  • Medical Advice

Always consult healthcare providers for personalized advice and plans, as they can offer medications and strategies designed for your specific needs. Healthcare professionals can provide guidance on symptom management, treatment adjustments, and supportive care to optimize quality of life during treatment.

Mental and Emotional Well-being

The psychological impact of pancreatic cancer is significant. Addressing mental and emotional health is as important as physical health.

  • Psychological Impact

Feelings of anxiety, depression, and fear are common. Acknowledging these emotions and seeking support can help manage them.

  • Support Systems

A strong support network is essential. Family, friends, and support groups offer both emotional support and practical help. Sharing experiences with others in similar situations can be particularly comforting.

  • Stress-Relief Techniques

Stress-relief techniques for managing pancreatic cancer include practices like meditation and mindfulness, which help reduce stress and promote calmness, engaging in enjoyable hobbies and interests for distraction and joy, and seeking support from mental health professionals such as therapists or counselors, which can be beneficial for emotional well-being.

Tips for Caregivers

Caregivers provide essential physical, emotional, and logistical support. Their involvement is crucial in the patient’s care journey.

Encouraging and assisting patients in following their nutritional and exercise plans can significantly impact their health. Preparing healthy meals, participating in exercise routines, and offering emotional support are practical ways to help.

Caregivers must also look after their own health. Taking breaks, seeking support from others, and engaging in self-care activities are vital to avoid burnout and maintain the ability to care for their loved ones.

 

Staying healthy and active while managing pancreatic cancer is challenging but achievable with the right strategies. Balanced nutrition, regular physical activity, and addressing mental well-being are key components. Caregivers play a crucial role and need to ensure they take care of themselves too. Remember, every step towards wellness counts, and with support from loved ones and healthcare professionals, it becomes easier to navigate this journey.

Join us in our mission to advance the early detection of pancreatic cancer and save lives. Explore www.trovanow.com to discover ways you can contribute and donate today. Your contribution can significantly impact the lives of pancreatic cancer patients and their families, providing hope and support for a brighter future.

 

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Research Spotlight: Cure Prize Team Leader Andrew Lowy, MD, PhD

Thanks to your generous support, at the end of last year Curebound announced funding for three Cure Prizes including a novel approach to treating pancreatic cancer led by Andrew Lowy, MD, PhD and his collaborators at UC San Diego and Salk Institute. This exciting research is advancing toward its first clinical trial.

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Is The Pancreatic Cancer Survival Rate Improving In 2024?

Pancreatic cancer is one of the most challenging forms of cancer due to its aggressive nature and typically late diagnosis. It accounts for approximately 3% of all cancers in the United States but is responsible for about 7% of all cancer deaths. This high mortality rate is primarily due to the difficulty of detecting the disease in its early stages. Symptoms often do not appear until the cancer is advanced, leading to a late diagnosis when treatment options are limited and less effective.

Understanding survival rates and the factors influencing them is crucial for patients, families, and healthcare providers. Survival rates offer a glimpse into the effectiveness of current treatment protocols and provide a benchmark for evaluating new therapies and interventions. For patients and their families, this information is essential for making informed decisions about treatment options and managing expectations.

Let’s explore whether the pancreatic cancer survival rate is improving in 2024. We’ll look at the latest statistics, new treatments, and the ongoing challenges.

Understanding Pancreatic Cancer

Pancreatic cancer starts in the tissues of the pancreas, an organ located in the abdomen behind the lower part of the stomach. It plays an essential role in digestion and blood sugar regulation. Pancreatic cancer is known for its rapid progression and often presents with nonspecific symptoms such as abdominal pain, weight loss, and jaundice. Risk factors include smoking, obesity, a family history of pancreatic cancer, and certain genetic syndromes.

The stages of pancreatic cancer range from Stage 0 (carcinoma in situ) to Stage IV (metastasized cancer). Early-stage detection significantly improves the chances of successful treatment, but unfortunately, most cases are diagnosed at a later stage.

Pancreatic Cancer Survival Rates

Historically, pancreatic cancer has had one of the lowest survival rates among major cancers. In the past decade, the five-year survival rate has been dismally low, often cited at around 10%. Several factors contribute to this, including late diagnosis due to the lack of specific symptoms and the aggressive nature of the cancer. Additionally, the pancreas’ location and its role in the body make surgical interventions complex and risky.

Efforts to improve survival rates have been ongoing, with researchers and clinicians focusing on early detection, novel treatment approaches, and personalized medicine. Early detection is critical because it allows for surgical removal of the tumor before it spreads. Advanced imaging technologies and blood tests for specific biomarkers are among the tools being developed to detect pancreatic cancer earlier.

Advances in Medical Research and Treatment

Recent years have seen significant advancements in pancreatic cancer research and treatment, offering hope for improved survival rates.

  • Early Detection and Screening

New imaging techniques and biomarkers are being developed to detect pancreatic cancer earlier. Liquid biopsies, which analyze blood for cancer cells or DNA, show promise in identifying cancer at an earlier, more treatable stage.

  • Personalized Medicine

Advances in genomics have allowed for more personalized treatment plans. By understanding the genetic mutations specific to an individual’s cancer, targeted therapies can be used to attack cancer cells more effectively while sparing healthy tissue.

  • Immunotherapy

Researchers are exploring various types of immunotherapy, including checkpoint inhibitors, vaccines, and adoptive cell transfer to determine which approaches are most effective for pancreatic cancer. Early clinical trials are promising and ongoing research reveals new ways to boost the immune system’s ability to target and destroy cancer cells.

  • Combination Therapies

Combining different types of treatments, such as chemotherapy with radiation or targeted therapy, has been shown to improve outcomes. Researchers are continually testing new combinations to find the most effective protocols.

Data and Statistics for 2024

As of 2024, preliminary data indicates a modest improvement in pancreatic cancer survival rates. The five-year survival rate has increased to approximately 12%, a slight but meaningful increase. This improvement can be attributed to earlier detection, better surgical techniques, and more effective treatment protocols. Additionally, efforts to increase awareness and early detection will be key in making sure that patients receive timely and effective treatment.

Comparing this data to previous years, we see a gradual but steady increase in survival rates. While the progress is slow, it is significant considering the aggressive nature of pancreatic cancer. With continued dedication and investment, there is hope for continued progress in the fight against pancreatic cancer.

Future Outlook

Collaboration among researchers, clinicians, and patients is essential for advancing our understanding and treatment of pancreatic cancer. By working together, we can pool resources, share insights, and accelerate progress towards improved outcomes for patients.

Participation in clinical trials is particularly important in driving innovation and advancing the field of pancreatic cancer treatment. Clinical trials offer patients access to cutting-edge therapies and experimental treatments that may not yet be widely available. Additionally, participation in clinical trials contributes valuable data to researchers, helping to refine treatment protocols and identify new avenues for exploration.

Join The Battle 

While pancreatic cancer remains one of the most challenging cancers to treat, there is hope. The survival rate for pancreatic cancer in 2024 shows a modest but encouraging improvement, thanks to advances in early detection, personalized medicine, and new treatment approaches. However, significant challenges persist, and continued research, funding, and awareness are critical to further progress.

As we look to the future, there is hope for continued progress in the fight against pancreatic cancer. With each new discovery and breakthrough, we move one step closer to more effective treatments and ultimately, improved survival rates for pancreatic cancer patients.

By working together and remaining committed to the goal of improving outcomes for pancreatic cancer patients, we can make meaningful strides towards a future where this devastating disease is more effectively treated and managed.

Supporting pancreatic cancer research and advocacy organizations also helps drive the progress needed to improve survival rates. Your contributions can fund critical research, support early detection initiatives, and provide essential resources for patients and families. Join us in our mission and donate today to advance the early detection of pancreatic cancer and save lives. Every contribution, regardless of the amount, makes a difference. Visit www.trovanow.com to learn how you can get involved and donate today. Together, we can make strides towards a future where pancreatic cancer is detected early and treated effectively.

 

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Life After Pancreatic Cancer: How To Move Forward

Surviving pancreatic cancer is a monumental achievement. With survival rates improving, albeit slowly, more individuals are living beyond this diagnosis. However, the journey doesn’t end with remission; in many ways, it just begins. The transition from being a patient to a survivor brings its own set of challenges and adjustments. Physical recovery, emotional well-being, lifestyle changes, and long-term health management are crucial components of this new phase. 

This blog aims to guide survivors through these aspects, providing practical advice, support, and inspiration to help you move forward confidently and healthily.

Physical Recovery and Health Management

  • Regular Medical Follow-Ups

Post-treatment, regular medical follow-ups are crucial. These check-ups typically include blood tests, imaging scans, and physical exams to monitor for recurrence and manage any ongoing side effects. The frequency of these visits may decrease over time, but their importance remains significant throughout your life. 

Establishing a strong relationship with your healthcare team is essential. This includes not just your oncologist, but also your primary care physician, nutritionist, and any other specialists involved in your care. Prepare questions in advance, bring a list of symptoms or side effects, and be proactive in discussing your concerns. It’s also helpful to keep a journal of any new symptoms or changes in your health, as this can provide valuable information to your healthcare team. These follow-ups are not only a chance to monitor your health but also an opportunity to receive reassurance and support. Regular interaction with your healthcare team helps ensure that any potential issues are caught early, which can significantly impact your long-term prognosis. Additionally, these visits can provide emotional comfort, as regular check-ups can help alleviate the anxiety many survivors feel about the possibility of recurrence.

  • Managing Side Effects

Survivors often face lingering side effects from treatment, such as fatigue, digestive issues, and pain. Managing these effectively requires a combination of medical intervention and lifestyle changes. Fatigue can be addressed through a balanced approach of rest and gentle exercise. Digestive issues are common due to the pancreas’s role in digestion, it may require dietary adjustments and medications. 

Specialized help is essential if you encounter severe or persistent side effects. Consult your healthcare provider for a customized plan and don’t hesitate to seek referrals to specialists, such as gastroenterologists, pain management experts or mental health professionals. Specialized rehabilitation services can also assist with physical and occupational therapy to address mobility issues and improve overall function.

  • Nutrition and Diet

Nutrition is crucial for recovery. A diet rich in fruits, vegetables, lean proteins, and whole grains supports overall health and helps manage digestive issues. Small, frequent meals can be easier to digest and help maintain energy levels. Consider consulting a dietitian who specializes in cancer recovery to create a personalized nutrition plan. Staying hydrated is equally important, especially if you’re dealing with digestive side effects.

Limiting processed foods, which are often high in sugar, unhealthy fats, and additives, is beneficial. Instead, focus on whole, unprocessed foods that provide natural nutrients. Cooking at home lets you choose ingredients and make healthier meals. Cooking and meal prepping can be therapeutic and help ensure you have healthy meals readily available. Consider preparing larger batches of food and freezing portions for days when you’re too tired to cook. Easy-to-prepare options like smoothies, soups, and salads can be both nutritious and convenient.

Emotional and Mental Health

  • Coping with Emotional Aftermath

The emotional impact of surviving cancer can be profound, often leading to anxiety, depression, or post-traumatic stress disorder (PTSD). Recognizing these feelings is the first step to managing them. Professional therapy or counseling can provide a safe space to process these emotions and develop coping strategies. Mindfulness practices, such as meditation and yoga, can also help reduce anxiety and promote mental well-being.

  • Support Networks

Building a strong support network is invaluable. Family and friends can offer emotional support, but connecting with others who have faced similar challenges can be particularly empowering. Support groups, both in-person and online, provide a platform to share experiences and gain insights. Many survivors find comfort in knowing they are not alone and can draw strength from the community. Participating in these groups can also provide practical advice on managing life after cancer.

Lifestyle Adjustments and New Beginnings

  • Physical Activity and Exercise

Regular physical activity is beneficial for cancer survivors, enhancing physical strength, reducing fatigue, and improving mood. Start with low-impact exercises such as walking, swimming or yoga and gradually increase the intensity as your stamina improves. Aim for at least 2-3 hours of moderate exercise per week, as recommended by health experts. Always consult your doctor before starting any new exercise regimen to ensure it’s safe for your specific condition.

  • Returning to Work

Deciding when and how to return to work can be challenging. Communicate openly with your employer about your needs and any accommodations that may be necessary, such as flexible hours or a modified workload. It’s important to ease back into your routine gradually, allowing your body and mind time to adjust. Balancing work with health priorities might require some trial and error, so be patient with yourself and seek support from colleagues or vocational counselors if needed.

  • Rediscovering Hobbies and Interests

Engaging in hobbies and activities you enjoy can significantly improve your quality of life. Whether it’s gardening, painting, reading or any other interest, these activities provide a sense of purpose and joy. Trying new hobbies can also be a rewarding way to discover new passions and skills. Staying motivated can be challenging, especially if you’re dealing with fatigue or other side effects, but setting small, achievable goals can help maintain momentum and provide a sense of accomplishment.

Long-Term Health and Wellbeing

  • Preventative Healthcare

Taking proactive steps to reduce the risk of recurrence is essential. Stay healthy by eating a balanced diet, exercising regularly, and avoiding smoking and excessive alcohol. Regular screenings and health check-ups are vital, even if you feel well. These preventative measures can help detect any issues early and provide peace of mind.

  • Setting Future Goals

Setting goals, both personal and professional, can give you direction and motivation. Start with small, attainable goals to build confidence and gradually set more ambitious ones. Whether it’s completing a marathon, learning a new skill or traveling to a new destination, having goals to strive for can be incredibly fulfilling. Celebrate each achievement, no matter how small, as a testament to your resilience and strength.

 

Surviving pancreatic cancer marks the beginning of a new chapter. By focusing on physical recovery, emotional well-being, lifestyle adjustments, and long-term health, you can move forward with confidence and hope. Life after cancer is a journey and it’s important to take it one step at a time. Surround yourself with supportive people, seek professional help when needed, and take proactive steps to maintain your health.

Giving is not just about making a donation, it’s about making a difference.​​​​​​​​ Join us in our mission and donate today to advance the early detection of pancreatic cancer and save lives. Visit www.trovanow.com to learn how you can get involved and donate today.

 

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What Does Life After-Treatment Of Pancreatic Cancer Look Like?

After the rigorous journey of pancreatic cancer treatment, survivors face a new chapter filled with its own set of challenges and opportunities. Let’s explore what life looks like post-treatment, offering insights and guidance to help pancreatic cancer survivors thrive. From physical recovery to emotional healing, the journey continues beyond the last treatment session. This period often brings a mix of relief, uncertainty and hope as survivors adjust to a “new normal” and strive to reclaim their lives. Understanding the unique aspects of life after treatment is essential for navigating this phase with strength and optimism. Through practical advice, emotional support and empowerment, this aims to encourage survivors to embrace their journey and live life to the fullest.

Life Immediately After Treatment

The aftermath of pancreatic cancer treatment often entails physical recovery and managing lingering side effects. Coping with fatigue, weakness, pain and changes in digestion requires patience and self-care. Establishing a routine that prioritizes rest, proper nutrition and gentle exercise can aid in the healing process during this phase. Additionally, reconnecting with loved ones and engaging in enjoyable activities or favorite hobbies can provide emotional support and uplift spirits during the transition from patient to survivor. It’s important for survivors to give themselves grace as they move through this period of adjustment and focus on rebuilding their strength and resilience.

Emotional and Mental Well-being

Emotional well-being is a crucial aspect of post-treatment life. Fear of recurrence, anxiety and depression are common challenges that survivors may face. It’s normal to experience a range of emotions as one faces the uncertainty of life after cancer. Seeking support from loved ones, joining support groups or seeking professional counseling can provide avenues for coping and healing. Building inner strength and maintaining a positive mindset are essential for emotional well-being. Mindfulness practices, journaling and relaxation techniques can also help manage stress and promote inner peace. By acknowledging and addressing their emotional needs, survivors can strengthen their mental well-being and enhance their overall quality of life.

Follow-Up Care and Monitoring

Regular check-ups and screenings are essential for monitoring health post-treatment. Healthcare providers play a crucial role in overseeing survivors’ ongoing care and addressing any concerns or symptoms that may arise. Understanding the importance of blood tests and imaging scans helps survivors stay vigilant about their well-being. Open communication with healthcare providers and recognizing signs of possible recurrence helps survivors take an active role in their own health. Additionally, maintaining a comprehensive medical history and staying informed about new developments in pancreatic cancer research can also help survivors to advocate for the future, their family, and make informed decisions about their care. By prioritizing follow-up care and monitoring, survivors can stay proactive in managing their health and minimizing the risk of recurrence.

Lifestyle Changes for Long-Term Health

Adopting a healthy lifestyle is key to long-term well-being. A balanced diet, rich in fruits, vegetables, whole grains and lean proteins, provides essential nutrients to support overall health and immune function. Avoiding processed foods, sugary beverages and excessive sodium and saturated fats can help reduce the risk of cancer recurrence and other chronic diseases. Regular exercise is also important for maintaining a healthy weight, improving cardiovascular health and boosting mood and energy levels. Even moderate physical activity, such as walking, swimming or yoga, can have significant benefits for survivors’ physical and mental well-being. Additionally, avoiding tobacco and limiting alcohol consumption further supports overall health and reduces the risk of cancer and other health problems. By making small, sustainable changes to their lifestyle, survivors can enhance their long-term health and quality of life.

Reintegrating into Daily Life 

Returning to work, pursuing hobbies and nurturing relationships are important aspects of post-treatment life. While it may take time to adjust to the demands of daily life, survivors can gradually return to their routines while prioritizing self-care and balance. Flexible work arrangements, such as part-time hours or telecommuting, may be helpful during the transition back to work. Exploring hobbies and interests that bring joy, excitement and fulfillment can provide a sense of purpose and identity beyond cancer. Nurturing relationships with family and friends and seeking support from loved ones can also help survivors feel connected and supported during this period of adjustment. By setting realistic goals, practicing self-compassion and celebrating their accomplishments, survivors can overcome the challenges of daily life with strength and hope.

Finding Meaning and Purpose 

Reflecting on the cancer experience, exploring spirituality or giving back to the community can provide a sense of meaning and purpose for survivors. Many survivors find that their cancer journey inspires them to make positive changes in their lives, pursue new goals or help others facing similar challenges. Engaging in activities that align with their values and passions can create a sense of fulfillment and empowerment. Whether it’s volunteering for a cancer support organization, participating in advocacy efforts or simply sharing their story with others, survivors can find purpose in making a difference in the lives of others. By embracing opportunities for personal growth, self-expression and contribution, survivors can find renewed meaning and purpose in life after cancer.

Life after pancreatic cancer treatment is a journey of healing and discovery. By embracing self-care, seeking support and pursuing a fulfilling life, survivors can face and overcome this chapter with hope for the future. Each day presents new opportunities for growth, connection and joy. With courage and determination, survivors can embrace their journey and thrive. As they continue to move forward, they carry with them the strength, wisdom and perseverance gained from their cancer experience, inspiring others and leaving a lasting legacy of hope and healing.

Join Us In The Fight Against Pancreatic Cancer

TrovaNow is dedicated to making a difference in the battle against pancreatic cancer. TrovaNow’s goal is to raise funds to support The Pancreatic Cancer Early Detection (PRECEDE) Consortium. PRECEDE brings together top experts from around the world to enhance early detection, screening and prevention strategies for individuals at high risk of pancreatic cancer. With TrovaNow’s support, PRECEDE aims to significantly improve survival rates and quality of life for pancreatic cancer patients.

Ready to make a difference in the fight against pancreatic cancer? Learn how you can contribute by visiting TrovaNow’s website at www.trovanow.com.

 

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Pancreatic Cancer & Genetics: What You Need To Know

Pancreatic cancer is one of the most aggressive and challenging cancers to diagnose and treat. Its unwanted distinction as the type of cancer with the lowest 5-year survival rate stems from late-stage detection and limited treatment options. However, recent research shows the significant role genetics play in the development of pancreatic cancer, offering insights that could potentially revolutionize early detection, prevention and treatment strategies. In this blog, let’s explore the important connection between pancreatic cancer and genetics, information that everyone should know.

Understanding Pancreatic Cancer

Pancreatic cancer arises when abnormal cells in the pancreas begin to grow uncontrollably forming tumors. Two primary types exist – exocrine tumors, which are more common and originate in the pancreatic ducts and neuroendocrine tumors, which develop from hormone-producing cells in the pancreas. Despite accounting for only a small percentage of all cancer cases, pancreatic cancer carries a disproportionately high mortality rate often due to its silent progression and lack of early symptoms. By the time symptoms manifest, the cancer has typically reached an advanced stage, making successful treatment challenging.

Genetic Factors in Pancreatic Cancer

Emerging evidence suggests that genetics is important in pancreatic cancer susceptibility. Certain inherited genetic mutations have been linked to an increased risk of developing the disease. Among the most notable are mutations in the BRCA1, BRCA2 and PALB2 genes which are traditionally associated with breast and ovarian cancers but also elevate the risk of pancreatic cancer. Individuals with a family history of pancreatic cancer are also at higher risk showing that the disease can run in families. Research indicates that other genetic factors such as variations in genes involved in DNA repair and cell growth regulation may also contribute to an individual’s predisposition to pancreatic cancer. Understanding these genetic influences is crucial for identifying high-risk individuals and implementing targeted screening and prevention strategies.

Genetic Testing for Pancreatic Cancer Risk

Genetic testing has become a powerful tool in assessing an individual’s risk of developing pancreatic cancer. It involves analyzing a person’s DNA to identify specific genetic mutations associated with increased cancer susceptibility. While genetic testing is not necessary for everyone, individuals with a family history of pancreatic cancer or those with known cancer-predisposing mutations may benefit from undergoing testing. By identifying high-risk individuals early on, healthcare providers can implement personalized screening and prevention strategies, potentially detecting cancer at its earliest, most treatable stages, improving the chances of successful treatment and better outcomes for patients.

Lifestyle and Environmental Factors

While genetics play a significant role in pancreatic cancer, lifestyle and environmental factors also contribute to disease development. Smoking, for instance, is a well-established risk factor, with smokers being up to three times more likely to develop pancreatic cancer than non-smokers. Obesity, chronic pancreatitis and a diet high in red and processed meats have also been linked to an increased risk. Although these factors may interact with genetic predispositions, they are largely modifiable, offering opportunities for individuals to reduce their risk through healthy lifestyle choices.

Screening and Prevention

Given the dire prognosis associated with pancreatic cancer, early detection is essential. Screening tests such as imaging studies and blood tests may be recommended for individuals at high risk, including those with a family history of pancreatic cancer or known genetic mutations. However, current screening methods are not without limitations, often detecting cancer at later stages when treatment options are limited. Thus, efforts to refine existing screening protocols and develop more sensitive diagnostic tools are ongoing. In the absence of effective screening methods for the general population, prevention remains a key focus, with lifestyle modifications and risk-reducing strategies are important in pancreatic cancer prevention efforts. These may include maintaining a healthy weight, avoiding tobacco use, limiting alcohol consumption and adopting a balanced diet rich in fruits and vegetables. By addressing modifiable risk factors, individuals can help reduce their likelihood of developing pancreatic cancer and improve their overall health outcomes.

Support and Resources

Coping with a pancreatic cancer diagnosis can be overwhelming, both for patients and their loved ones. Fortunately, numerous support resources are available to guide, assist and provide emotional support throughout the journey. These organizations offer valuable resources, including educational materials, support groups and patient services. Online communities and forums provide platforms for individuals to connect with others facing similar challenges, building a sense of companionship and understanding.

As our understanding of pancreatic cancer continues to evolve, it becomes increasingly evident that genetics play an important role in disease development. By understanding the genetic basis of pancreatic cancer, researchers are leading the way for more personalized approaches to screening, prevention and treatment. While genetic testing holds promise in identifying high-risk individuals, it is essential to recognize the interplay between genetics, lifestyle and environmental factors in shaping pancreatic cancer risk. By embracing a holistic approach to disease prevention and management, we can strive towards a future where pancreatic cancer is not only detectable but also preventable.

TrovaNow is here to help. TrovaNow’s goals is to raise funds to support the Pancreatic Cancer Early Detection (PRECEDE) Consortium. PRECEDE is an international, multi-institutional collaborative consortium of world-renowned experts in pancreatic cancer. Its goal is to increase survival for patients by improving early detection, screening, risk modeling and prevention for those with a heritable risk for pancreatic cancer, through a novel model of collaboration and data sharing. With over 40 leading academic medical centers across the globe, PRECEDE has assembled the largest high-risk patient cohort with biospecimen collection and longitudinal clinical data.

TrovaNow’s mission is to increase the 5-year survival rate from 13% to 50% in the next 10 years through early detection and prevention of pancreatic cancer. With a dedicated focus on advancing research, education and support initiatives, TrovaNow is committed to making a meaningful impact in the fight against pancreatic cancer. 

You can be a part of this mission by donating and getting involved today! Visit TrovaNow’s website www.trovanow.com to learn more about how you can contribute and make a difference in the lives of those affected by pancreatic cancer. Your support keeps pancreatic cancer research going, driving us closer to our goal of improving survival rates and providing hope to those affected by this disease.

 

Visual related to 2024 health & wellness checklist

2024 Health & Wellness Checklist

In the pursuit of a healthier 2024, it’s crucial to prioritize preventive health measures and screenings. This checklist is designed to guide you through key steps to incorporate into your routine, ensuring an active approach to your well-being. 

As a committed advocate for health and wellness, TrovaNow recognizes the importance of empowering individuals to take control of their health journey. By providing accessible and actionable information, we aim to support you in making informed decisions and encouraging a lifestyle that promotes long-term vitality and happiness. Let’s explore this journey together towards a healthier and happier 2024.

  • General Health Checkpoints

Begin with regular health check-ups and screenings to establish a baseline for your well-being. These assessments provide valuable insights into your health status and help detect potential issues early. Maintaining a balanced and nutritious diet is equally essential, supporting overall vitality. Additionally, incorporating physical activity into your routine contributes to holistic well-being. It’s also important to prioritize adequate hydration, ensuring your body functions optimally. Getting enough sleep and managing stress levels are key components of maintaining good health. Moreover, practicing good hygiene habits, such as regular handwashing, can help prevent the spread of infections and illnesses. Taking steps to address any health concerns promptly ensures you stay on track toward optimal well-being.

  • Cardiovascular Health

Take charge of your cardiovascular health by monitoring blood pressure regularly. Check cholesterol levels and lipid profiles and adopt heart-healthy lifestyle choices such as consuming a diet rich in fruits, vegetables and whole grains, while limiting saturated and trans fats. Engaging in regular physical activity, such as brisk walking, cycling or swimming, can also strengthen your heart and improve overall cardiovascular health. Understanding the importance of these measures helps you make informed decisions for a healthier heart and reduces the risk of heart disease and related complications.

  • Metabolic Health

Prioritize blood sugar monitoring and implement preventive measures for diabetes, such as maintaining a balanced diet low in added sugars and refined carbohydrates. Manage your weight through a combination of healthy eating and regular exercise, aiming for at least 30 minutes of moderate-intensity activity most days of the week. Focusing on metabolic health not only reduces the risk of developing diabetes but also enhances your body’s resilience against various health challenges.

  • Mental Health and Well-Being

Recognize the significance of mental health by practicing stress management techniques such as deep breathing exercises, meditation or yoga. Incorporate mindfulness and relaxation into your daily life by setting aside time for activities that bring you joy and peace, such as spending time in nature, listening to music or practicing hobbies. It is important to recognize that mental health plays an integral role in overall wellness. By prioritizing mental well-being alongside physical health, you can cope better with life’s challenges. Remember to take care of your mind as well as your body, as they are interconnected aspects of your overall health and happiness.

  • Lifestyle Choices 

Quality sleep is essential for overall well-being, as it allows your body to rest and rejuvenate. Limiting alcohol consumption and avoiding tobacco use are also crucial lifestyle choices for promoting longevity and reducing the risk of chronic diseases. Strive to maintain a healthy work-life balance by setting boundaries and prioritizing self-care activities. Recognize the impact of lifestyle on your health journey, and make mindful choices that support your physical and emotional well-being.

  • Immunizations and Vaccinations

Stay up-to-date with recommended vaccinations for your age group to protect yourself and others from preventable diseases. Getting immunizations is a vital aspect of preventive health, as it helps to build immunity and prevent the spread of infectious illnesses. By staying informed and receiving necessary vaccinations, you not only safeguard your own health but also contribute to community immunity, protecting those who may be more vulnerable to infections.

  • Eye and Dental Health

Regular eye check-ups and dental care are essential components of your health routine. Prioritize vision and oral well-being for a comprehensive approach to health, as they are crucial aspects of overall well-being. Vision problems can impact daily activities and quality of life, while oral health issues can lead to discomfort, pain and even systemic health problems if left untreated. By scheduling regular dental check-ups and practicing good oral hygiene, you can maintain oral health, reducing the risk of dental problems and supporting your overall well-being. Remember, taking care of your eyes contributes to your long-term health and quality of life.

  • Cancer Prevention

Stay informed about cancer screenings and incorporate them into your routine. Lifestyle factors, including a healthy diet and regular exercise, play an essential role in preventing various types of cancer, such as pancreatic cancer. Know your own family history and talk to your physician about assessing your risk for pancreatic cancer. TrovaNow’s mission is dedicated to advancing early detection and treatment of pancreatic cancer, aiming to transform this disease and improve pancreatic cancer survival rates. Pancreatic cancer is often diagnosed at advanced stages, making it a formidable foe. By highlighting the connections between pancreatic cancer and overall health, we emphasize the significance of early detection and take steps to manage this challenging condition. Incorporating these preventive measures into your health routine helps you to take control of your well-being and reduce your risk of developing cancer.

Remember, your well-being is a journey and every step counts toward a healthier you. Use this checklist to improve your health in 2024. TrovaNow is dedicated to supporting individuals, especially in understanding and managing pancreatic cancer, which aligns with your commitment to staying healthy.

When you choose hope, anything is possible.

At TrovaNow, we’re on a mission to raise funds for collaborative research aimed at early detection and prevention. Our goal is to increase the 5-year survival rate from 12% to 50% within the next decade. Proceeds from TrovaNow contribute to research efforts focused on detecting pancreatic cancer earlier, potentially saving thousands of lives from the deadliest cancer.

TrovaNOW is raising funds for the PRECEDE Consortium, a group of leading experts and organizations dedicated to advancing research and innovation in pancreatic cancer prevention and pancreatic cancer early detection. This partnership allows us to leverage the collective expertise and resources in the fight against cancer, ensuring a more comprehensive and impactful approach to addressing the challenges posed by this devastating disease. Join us in supporting this critical effort to revolutionize pancreatic cancer prevention and early detection.

Visit www.trovanow.com to learn how you can get involved and donate today.

 

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The Connection Between Pancreatic Cancer And Other Health Conditions

Pancreatic cancer remains one of the most challenging and devastating forms of cancer, often diagnosed at an advanced stage with limited treatment options. The pancreas, an important organ behind the stomach, helps with digestion and regulates blood sugar. When pancreatic cancer strikes, its stealthy progression often leads to late-stage diagnosis, contributing to its high mortality rate. However, beyond its isolated impact on the pancreas, emerging research suggests a profound connection between pancreatic cancer and other health conditions. 

In this blog, we’ll explore the connections between various aspects of health with a focus on relationships related to pancreatic cancer and highlighting the crucial role of holistic well-being.

The Complexity of Pancreatic Cancer

Pancreatic cancer, characterized by the uncontrolled growth of cells in the pancreas, poses significant challenges due to its aggressive nature. The pancreas itself is a multifunctional organ, contributing to both the endocrine and exocrine systems. As pancreatic cancer progresses, its impact extends beyond the organ, influencing overall bodily functions.

Pancreatic cancer poses a unique set of challenges due to its asymptomatic nature in its early stages. Symptoms may not manifest until the disease has advanced, making early detection a considerable challenge. The limited treatment options make it even more challenging to manage this formidable adversary. Understanding the complexity of pancreatic cancer is essential to appreciate the broader impact it can have on the body.

Beyond The Pancreas: Understanding The Connections

To understand how pancreatic cancer affects everything around it, it is crucial to understand the pancreas’s normal functions and its role in maintaining homeostasis. The pancreas secretes enzymes essential for digestion and regulates blood sugar levels through insulin production. When cancer disrupts these functions, it sets off a cascade of effects throughout the body.

Recent studies have uncovered connections between pancreatic cancer and various health conditions, exploring how things work inside the body. As we explore, we want to uncover connections beyond the pancreas, showing the importance of understanding overall health.

The challenge in managing pancreatic cancer lies in its late-stage diagnoses, often when the cancer has metastasized. At this advanced stage, treatment options are limited and the prognosis becomes more daunting. Exploring the impact on overall health requires acknowledging the consequences of late-stage interventions.

Common Health Conditions Linked to Pancreatic Cancer

Beyond its direct consequences, pancreatic cancer exhibits connections with other health conditions, creating a complex network of influences. Diabetes, chronic pancreatitis and obesity are important parts of this interconnected web.

  1. Diabetes: The link between diabetes and pancreatic cancer goes beyond a simple association. Not only does diabetes increase the risk of developing pancreatic cancer, but the cancer itself can induce diabetes through its impact on insulin-producing cells. This bidirectional relationship highlights the complex dynamics in action.

Recognizing the bidirectional nature of the relationship between pancreatic cancer and associated health conditions is essential. Diabetes can both contribute to and result from pancreatic cancer, emphasizing the need for a detailed understanding of these complex interactions.

  1. Chronic Pancreatitis: Chronic inflammation of the pancreas, known as pancreatitis, serves as a precursor to pancreatic cancer. The prolonged inflammatory state creates an environment conducive to cancer development, emphasizing the importance of addressing inflammation in holistic health approaches.

The coexistence of health conditions can exacerbate the risk and progression of pancreatic cancer. Individuals with a history of diabetes or chronic pancreatitis may require vigilant monitoring and early intervention to address potential cancer development. This interconnectedness amplifies the importance of holistic health strategies.

  1. Obesity: Obesity, recognized as a risk factor for various cancers, including pancreatic cancer, involves many different factors interacting with each other. Excess adipose tissue, inflammation and insulin resistance contribute to the heightened risk, illustrating the need for holistic interventions to address these interconnected issues.

Holistic Health

Holistic health transcends the conventional approach of treating isolated symptoms. It involves considering the interconnectedness of physical, mental and emotional well-being, recognizing that the body functions as a complex and integrated system.

Adopting a holistic approach is particularly relevant in pancreatic cancer and associated health conditions. By addressing lifestyle factors, mental health and overall wellness, individuals can enhance and strengthen their ability to cope and reduce the risk of developing or exacerbating health issues.

Pancreatic cancer affects more than just the body, affecting mental and emotional well-being. The stress and emotional toll of dealing with a cancer diagnosis require holistic interventions to support individuals in many ways.

Lifestyle Choices and Their Impact

  • Unhealthy Lifestyle Choices: Smoking and excessive alcohol consumption are known risk factors for pancreatic cancer. By making informed choices, individuals can significantly reduce their risk and contribute to their overall health.
  • Importance of Regular Check-Ups: Routine health check-ups provide an opportunity for early detection and intervention. Individuals with a family history of pancreatic cancer or predisposing health conditions should be particularly vigilant, emphasizing the significance of proactive healthcare and screening.
  • Expert Perspectives: Engaging with the perspectives of medical professionals provides a deeper understanding of the link between pancreatic cancer and overall health. Expert insights guide individuals in adopting evidence-based holistic approaches to enhance their well-being.
  • Recommendations for a Holistic Approach: Healthcare experts can offer practical recommendations for integrating holistic health strategies into daily life. These recommendations serve as a roadmap for individuals seeking to proactively manage their health.

The Role of Pancreatic Cancer Early Detection

Early detection remains a critical factor in managing pancreatic cancer. Regular screenings, particularly for individuals with predisposing health conditions, can lead to early intervention and improved outcomes.

Adopting a proactive approach to health through lifestyle modifications, regular check-ups and awareness of risk factors can contribute to the prevention of pancreatic cancer and associated health conditions.

Pancreatic Cancer and Early Detection

TrovaNow in collaboration with the PRECEDE consortium, offers innovative tools and resources for early detection. These initiatives empower individuals to stay vigilant and proactive in safeguarding their health. TrovaNow and the PRECEDE Consortium are working hard to develop tools for early detection that will help to increase the survival rate for pancreatic cancer. 

Remember that pancreatic cancer is connected to overall health. It’s important to see the big picture and take charge of your well-being. Choose wisely, reduce risks and stay healthy. 

Hope for the future starts with you. With more research and funding, fewer lives will be taken. Join us in our mission to advance the detection and treatment of pancreatic cancer.