Jaundice: A Vital Early Warning Sign for Pancreatic Cancer — Insights from Diane Simeone, MD

August 7, 2025
Precede Foundation

We are pleased to share that Dr. Diane Simeone, Chief Scientific Advisor to the Precede Foundation and founding director of the PRECEDE consortium, was recently spotlighted in a New York Post article published on August 5, 2025. In the feature, Dr. Simeone underscores how jaundice—yellowing of the skin and eyes—is one of the most telling early signs of pancreatic cancer, a disease notorious for its subtle onset and low five‑year survival rate. Below, you’ll find a curated excerpt capturing her insights; or click here to read the full article for additional context and details.

Pancreatic cancer remains one of the most lethal cancers, with only about a 13 percent five‑year survival rate, largely due to its frequently silent early stage. In a recent New York Post article published on August 5, 2025, Dr. Diane Simeone—Chief Scientific Advisor and founding director of the Pancreatic Cancer Early Detection Consortium (PRECEDE)—emphasizes that jaundice, marked by yellowing of the skin or eyes, is among the most distinctive and potentially life-saving early indicators of pancreatic cancer.

Because tumors often develop deep within the pancreas, symptoms such as fatigue, unexplained weight loss, or digestive discomfort are typically vague and easily misattributed. Jaundice more reliably points toward a tumor obstructing the bile ducts, leading to bilirubin buildup. Additional red flags include dark urine, pale stools, itchy skin, and abdominal discomfort.

Dr. Simeone also highlights PRECEDE’s mission: to elevate the five‑year survival rate from 13 percent to 50 percent by standardizing early screening protocols, validating biomarkers, and accelerating the development of early detection tools—potentially including a blood‑based test.

Knowing When To Ask For Help

There’s strength in recognizing when you need additional support. If you’re feeling consistently overwhelmed, anxious, or depressed, it may be time to speak with a healthcare professional. Warning signs can include ongoing sleep trouble, loss of appetite, or emotional numbness.

Mental health care is an important part of cancer recovery. There are therapists, social workers, and cancer-specific counselors trained to support your unique needs. Don’t hesitate to seek them out.

Your medical team can help adjust medications or recommend physical therapy if your symptoms are impacting your daily life. Being honest about your struggles allows your care providers to offer better, more personalized support.

The path to recovery from pancreatic cancer is rarely straightforward. It’s a mix of triumphs and setbacks, strength and vulnerability. But through each high and low, healing is happening. Be gentle with yourself. Allow space for rest, reflection, and growth.

You don’t have to go through this journey alone. With the right support, emotional, physical, and practical, you can move forward, one step at a time. And remember, every day you show up for yourself is a victory.

At TrovaNOW, we’re focused on finding a cure for pancreatic cancer. Every test and discovery brings us closer to better treatments and saving lives. Join us and learn more at TrovaNOW.

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Setting Recovery-Focused New Year’s Resolutions

The New Year often inspires reflection, hope, and the opportunity to turn a fresh page. For individuals managing chronic illnesses, this time can be particularly empowering. It offers a moment to prioritize recovery, focus on what truly matters, and set resolutions that improve your physical and mental well-being. If you’ve been hesitant about making New Year’s resolutions in the past, let’s explore how a recovery-focused approach can transform your outlook.

Why Recovery-Focused Resolutions Matter

Resolutions often falter because they’re overly ambitious or lack a clear purpose. But recovery-focused resolutions have a distinct edge: they’re deeply personal, grounded in self-care, and aimed at achievable progress. These goals prioritize your health journey, allowing you to celebrate small victories while working towards long-term well-being.

Chronic illnesses can feel overwhelming, but by breaking goals into manageable steps, you regain control over your life. Recovery isn’t a one-size-fits-all journey, and resolutions tailored to your unique needs can be a powerful motivator. For those managing conditions such as pancreatic cancer, these steps are vital to maintaining both physical and emotional health.

1. Start Small and Stay Realistic

One of the most important things to remember is to start with manageable goals. Overloading yourself with a long list of drastic changes can lead to frustration. Instead, focus on setting SMART goals: Specific, Measurable, Achievable, Relevant, and Time-bound.

  • Example: Instead of “I’ll start exercising every day,” try “I’ll take a 10-minute walk three times a week.” Small, consistent steps create sustainable habits.
  • Pro Tip: Celebrate milestones along the way. That sense of accomplishment fuels motivation and reminds you that progress matters, not perfection.

2. Reframe Self-Care as Essential, Not Optional

Self-care isn’t indulgent; it’s a critical component of recovery. Chronic illnesses can deplete your energy and emotional reserves, so prioritizing self-care is non-negotiable. Incorporate these practices into your resolutions:

  • Prioritize Sleep: Create a bedtime routine that supports quality rest. Limit screen time, dim the lights, and aim for 7-9 hours of sleep each night.
  • Practice Stress Management: Explore relaxation techniques like deep breathing, meditation, or journaling. Even 5 minutes a day can make a difference.
  • Nourish Your Body: Focus on adding nutrient-dense foods to your meals, such as leafy greens, whole grains, and lean proteins. If you’re managing conditions like pancreatic cancer, explore foods for pancreatic cancer or a tailored healthy diet for pancreatic cancer patients to support healing and improve energy levels.

3. Embrace Movement on Your Terms

Exercise can feel daunting, especially when you’re managing a chronic condition. The key is to redefine movement to suit your body’s capabilities and needs.

  • Gentle Activities: Consider yoga, tai chi, or swimming—low-impact options that promote flexibility and strength without overexertion.
  • Listen to Your Body: Some days will feel better than others. Honor what your body is telling you and adapt your routine accordingly.
  • Set Enjoyable Goals: Choose activities you genuinely enjoy. This increases the likelihood of sticking to them long-term.

4. Build a Support System

You don’t have to navigate recovery alone. A strong support network can provide encouragement, advice, and a sense of belonging. Consider these steps:

  • Lean on Loved Ones: Share your goals and progress with family and friends. Open communication fosters understanding and accountability.
  • Join Support Groups: Many chronic illnesses, including pancreatic cancer, have online or local support groups. These communities can offer practical advice and emotional solidarity.
  • Seek Professional Guidance: Don’t hesitate to involve healthcare providers, nutritionists, or physical therapists in your recovery plan. Their expertise ensures your goals are safe and tailored to your condition.

5. Find Joy in the Journey

Life with a chronic illness isn’t all about restrictions and routines. Finding joy in the little things can boost your mental health and resilience.

  • Explore New Hobbies: Creative pursuits like painting, cooking, or gardening can provide a therapeutic outlet.
  • Connect with Nature: Spend time outdoors when possible. A walk in the park or sitting in your garden can lift your mood and reduce stress.
  • Celebrate Progress: Keep a journal to track small wins. Reflecting on how far you’ve come can be a powerful motivator.

6. Stay Flexible and Kind to Yourself

Recovery is rarely linear. Setbacks and tough days are inevitable, but they don’t erase your progress. Practicing self-compassion is vital:

  • Be Adaptable: Adjust your goals as needed. Life happens, and flexibility ensures you stay on track without unnecessary pressure.
  • Forgive Yourself: If you miss a day or fall short of a goal, let it go. Tomorrow is another chance to try.
  • Remember Your Why: Keep the bigger picture in mind. Remind yourself why you’ve chosen these resolutions and the benefits they bring to your health.

Supporting Pancreatic Cancer Research and Awareness

As you set your recovery-focused resolutions, consider ways to give back and support others on similar journeys. If you’re inspired to help, you can donate to pancreatic cancer research or explore pancreatic cancer donation sites like TrovaNow. Every contribution, whether it’s a pancreatic cancer research donation or spreading awareness about early detection pancreatic cancer, helps move us closer to breakthroughs in treatment and care.

Here are actionable ways to make a difference:

  • Donate to Early Detection Pancreatic Cancer: Funding research for early detection saves lives by identifying symptoms sooner.
  • Support Pancreatic Cancer Charities in the USA: Organizations like the PRECEDE Consortium and others lead vital studies and support networks.
  • Promote Pancreatic Cancer Awareness: Share information on warning signs of pancreatic cancer, such as fatigue, unexplained weight loss, and pancreatic cancer blood clots.

A New Year, a Renewed You

Recovery-focused New Year’s resolutions aren’t just about ticking boxes—they’re about reclaiming your sense of purpose, health, and joy. As you enter this new chapter, remember that every small effort adds up. By prioritizing achievable goals, embracing self-care, and leaning on your support network, you’re setting yourself up for a brighter, healthier year ahead.

So here’s to you—taking the reins, embracing your journey, and stepping into the New Year with hope and determination. Let’s make this one count.

Visit TrovaNow for more inspiration, resources, and tools to help you navigate your recovery journey with confidence. Together, let’s make a difference.

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Precede Annual Meeting 2024

Nation’s Largest Pancreatic Cancer Early Detection Study Holds Annual Meeting in San Diego

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Essential Guide For Returning To Work After Cancer

Returning to work after a diagnosis of pancreatic cancer can be a challenging experience. The journey through diagnosis, treatment, and recovery is difficult, and the transition back to the workplace often brings mixed emotions. This guide aims to provide essential information and support for individuals managing this significant life change, promoting a more manageable return to work.

1 – Consultation With Healthcare Professionals

Before making any decisions about returning to work, it’s important to consult with your healthcare team. Follow-up appointments after treatment are crucial for assessing your overall health and recovery status. These appointments not only help monitor your physical well-being but also provide an opportunity to address any lingering symptoms or side effects that could impact your work life.

Discuss your readiness for work with your doctors, including any physical limitations, ongoing treatments, or medications that may affect your work capacity. If you’re experiencing fatigue, pain, or cognitive challenges, it’s essential to communicate these issues to your healthcare provider. They can help you determine whether a gradual return to work is appropriate and suggest specific accommodations that may be necessary for your success in the workplace.

2 – Assessing Physical And Emotional Health

As you prepare to return, take time to evaluate both your physical and emotional well-being. Pancreatic cancer treatment often leads to fatigue and stamina issues, which can impact your ability to work. Pay attention to your energy levels and how you feel on a day-to-day basis. Emotional readiness is just as important, consider how you’re coping with the emotional challenges of recovery. Support from mental health professionals may be beneficial as you adjust.

3 – Communicating With Your Employer

Open communication with your employer is essential for a successful transition back to work. Prepare for a conversation with your Human Resources (HR) department and your direct manager about your return. Be honest about your health status and discuss any accommodations you might need, such as flexible hours, a gradual return to full-time, or modified duties. Many employers are willing to work with you to create a supportive environment.

Familiarize yourself with your rights as a cancer survivor in the workplace. Laws such as the Americans with Disabilities Act (ADA) protect employees from discrimination and provide for reasonable accommodations. Knowing your rights can enable you during discussions with your employer and help ensure that you receive the support you need.

4 – Preparing For The Return

A gradual transition back to work can make the adjustment smoother and help you rebuild confidence in your routine. Consider discussing a phased return-to-work plan with your employer, starting with part-time hours or taking on specific tasks that allow for flexibility. This approach provides time to readjust to the demands of work while closely monitoring your health, energy levels, and any side effects from treatment. Open communication with your employer and colleagues about your needs can set a positive tone, making the transition feel collaborative and supportive.

Creating a comfortable and accessible workspace is equally important for a successful return. Evaluate your work environment and consider adjustments to accommodate your physical needs, such as ergonomic furniture, flexible seating, or equipment that reduces physical strain. If mobility is an issue, assess accessibility within your workspace, from desk arrangement to the layout of common areas. These adjustments not only support physical comfort but can also help reduce stress, enhance focus, and make the workday more manageable.

5 – Managing Work-Life Balance

As you transition back to work, effective time management will be crucial. Prioritize tasks to focus on what is most important and manageable. Use tools like calendars or task management apps to help stay organized. Setting realistic goals and breaking larger projects into smaller, manageable tasks can prevent feeling overwhelmed.

Incorporating self-care into your daily routine is essential for maintaining your well-being. Find strategies for stress management that work for you, such as meditation, exercise, or spending time with loved ones. Schedule regular breaks throughout your workday to recharge and prevent burnout. Remember, taking care of your mental and physical health is a priority during this time.

6 – Building A Support Network

Re-establishing connections with your coworkers can provide a strong support system as you return to work. Maintain open communication with your colleagues about your situation, they may offer understanding and assistance. If your workplace has an Employee Assistance Program (EAP), take advantage of it for additional resources and support.

Consider joining support groups for cancer survivors, either in person or online. These groups can provide valuable resources, shared experiences, and emotional support. Connecting with others who have faced similar challenges can help you feel less isolated and offer practical advice for managing your return to work.

7 – Resources And Tools

There are many organizations dedicated to supporting cancer survivors and their families. Organizations provide resources, advocacy, and community support. They often offer information on managing work-related challenges and may connect you with others who have similar experiences.

Exploring online resources and forums can also be beneficial. Websites that offer valuable information on returning to work, managing stress, and coping with the effects of cancer. Participating in forums can provide a sense of community and allow you to exchange experiences and strategies with others.

 

Returning to work after pancreatic cancer is a significant step in reclaiming your life and routine. By understanding your health status, communicating with your employer, preparing for the transition, and building a support network, you can face this journey with confidence. Remember that it’s okay to ask for help and take things one step at a time. You are not alone in this journey, and there are resources and people available to support you every step of the way.

At TrovaNow, we are dedicated to supporting individuals recovering from cancer and facing new life transitions. Our mission is to provide each person on their wellness journey with valuable information and guidance suited to their needs. If this guide has been helpful, consider joining us in our commitment to promoting early detection and prevention of pancreatic cancer. Visit www.trovanow.com to learn how you can get involved and donate today to support cancer survivors and their families in building healthier, stronger futures.