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Pancreatic cancer is a malignant tumor that develops in the pancreas, a vital organ located behind the stomach. It is often referred to as a “silent killer” due to its subtle symptoms in the early stages, leading to delayed diagnosis and poor prognosis. In the aging population, the incidence of pancreatic cancer increases significantly, especially in individuals over the age of 65.

Pancreatic cancer is a challenging and often devastating disease that affects people of all ages. However, it is more prevalent among the aging population, with a higher incidence and mortality rates observed in older adults. As life expectancy continues to rise, understanding the unique challenges and opportunities for early detection in this demographic becomes crucial. Explore the complexities of pancreatic cancer in the aging population and the potential strategies for improving early detection and patient outcomes.

I. Importance of Early Detection in Improving Outcomes

As people age, the incidence of pancreatic cancer increases, peaking in individuals over 80. Aging involves cellular changes and genetic mutations that raise the risk of cancer development. Additionally, older adults may have weaker immune systems, making them more susceptible to cancer progression.

Several risk factors contribute to pancreatic cancer in older adults, such as smoking, family history, obesity, diabetes, chronic pancreatitis, and certain genetic syndromes. Identifying these factors helps healthcare providers assess the likelihood of developing the disease and customize screening and prevention.

Early detection plays a crucial role in improving the prognosis and overall survival of pancreatic cancer patients. When the disease is diagnosed at an early stage, treatment options are more effective and offer a higher chance of successful outcomes. However, detecting pancreatic cancer early in older adults can be particularly challenging due to various factors, including age-related symptoms, comorbidities, and screening limitations.

II. Challenges in Diagnosing Pancreatic Cancer in Older Adults

One of the main challenges in diagnosing pancreatic cancer in older adults lies in the overlap of symptoms with age-related conditions and comorbidities. For example, weight loss, fatigue, and gastrointestinal symptoms may be attributed to other chronic illnesses, delaying the recognition of pancreatic cancer.

Screening for pancreatic cancer in older adults presents certain challenges due to the invasiveness and cost of imaging techniques such as endoscopic ultrasound and magnetic resonance cholangiopancreatography (MRCP). Additionally, older individuals may have multiple health issues, making them less likely to undergo extensive screening procedures.

III. Opportunities for Early Detection

• Emerging Biomarkers and Imaging Techniques for Early Diagnosis

Medical research has identified potential biomarkers and imaging techniques for early detection of pancreatic cancer. Biomarkers like CA 19-9 and CEA can identify high-risk individuals and monitor treatment response. Non-invasive imaging techniques such as contrast-enhanced CT and PET have shown promise in detecting early-stage tumors.

• The Role of Genetic Testing and Personalized Medicine in High-Risk Individuals

Genetic testing can identify individuals with a family history of pancreatic cancer or genetic syndromes that predispose them to the disease. Early identification of high-risk individuals allows for personalized surveillance and preventive measures, potentially leading to earlier diagnosis and improved outcomes.

IV. Managing Treatment Decisions in Older Adults with Pancreatic Cancer

The treatment plan for older adults with pancreatic cancer carefully considers their overall health and life expectancy. The medical team assesses the benefits and side effects of options like surgery, chemotherapy, radiation therapy, and immunotherapy to prioritize the patient’s quality of life.

Personalized care that considers the patient’s preferences, goals, and values is essential in providing comprehensive treatment for older adults with pancreatic cancer. Shared decision-making involving the patient, their family, and the healthcare team helps ensure that treatment choices align with the patient’s wishes.

V. Supportive Care and Quality of Life for Older Patients

A cancer diagnosis can have a profound emotional impact on both patients and their families. Older adults may face additional challenges in coping with the disease, including concerns about caregiving and end-of-life decisions. Providing psychological support and counseling can help patients and their families manage the emotional complexities of pancreatic cancer.

Palliative care plays a crucial role in managing symptoms, alleviating pain, and improving the overall quality of life for patients with pancreatic cancer, particularly for those in advanced stages. Integrating palliative care early in the treatment process can significantly enhance patient well-being.

VI. Lifestyle and Prevention Strategies for the Aging Population

Promoting healthy lifestyle choices such as regular exercise, a balanced diet and smoking cessation are critical to mitigate the risks of a variety of health issues. Regular health screenings for pancreatic cancer and other conditions along with timely attention to potential warning signs can lead to early intervention and better treatment outcomes.

VII. Collaboration and Awareness

Providing comprehensive care for older adults with pancreatic cancer requires collaboration among various healthcare specialists, including oncologists, geriatricians, surgeons, nurses, and palliative care providers. This interdisciplinary approach ensures that the patient’s unique needs are addressed from multiple perspectives. 

Increasing public awareness about the prevalence and risk factors of pancreatic cancer in the aging population is crucial in promoting early detection and timely intervention. Educating both older adults and healthcare professionals can lead to better recognition of symptoms and more proactive health-seeking behaviors.

Pancreatic cancer in the aging population poses significant challenges but also presents opportunities for improving early detection and patient outcomes. By recognizing the unique risk factors and screening limitations in older adults, healthcare providers can develop targeted strategies for timely diagnosis and personalized care. With advancements in research and technology, combined with a collaborative and comprehensive approach to care, a future with early detection and improved outcomes for older adults with pancreatic cancer is within reach. By joining hands and advocating for awareness, we can make a significant difference in the lives of older patients and their families, empowering them to face pancreatic cancer with hope.

Sadly, pancreatic cancer still has one of the lowest 5 year survival rates of any kind of cancer, at about 12%. Help increase the 5-year survival rate from 12% to 50% in the next decade. 

Together, let’s gift the world with hope and a brighter future. Donate to TrovaNOW and support early detection and prevention of pancreatic cancer. Visit www.trovanow.com to get involved and donate today.

Pancreatic cancer comes with numerous challenges, and it’s essential to be mindful of your nutrition to boost your overall health and well-being. Proper nourishment can help in the management of symptoms, support healing, and improve your quality of life. Join us as we delve into ten important dietary recommendations to help you maintain good nutrition while living with pancreatic cancer.

• Prioritize a Balanced Diet: Good nutrition is crucial for the body’s healing and recovery processes. The right food choices can enhance the quality of life for individuals with pancreatic cancer. 

A well-balanced diet involves consuming whole grains, lean proteins, healthy fats, fruits, and vegetables, providing essential nutrients, antioxidants, and fiber that support the immune system, reduce inflammation, and promote overall health and well-being. Adequate intake of protein, vitamins, and minerals supports tissue repair and rebuilding, helps boost the immune system, and enhances the body’s ability to recover from the effects of pancreatic cancer treatments.

Enjoying nutritious and flavorful meals can improve mood, provide a sense of pleasure and comfort, and contribute to an overall positive outlook.

• Eat Smaller, Frequent Meals: Pancreatic cancer treatments can cause digestive issues such as poor appetite, nausea, bloating, and discomfort.

To prevent these symptoms consuming smaller, more frequent meals throughout the day can provide your body with the necessary nutrition to ensure you get enough nutrients and calories without overloading your digestive system. Instead of having three large meals, aim for five to six smaller meals or snacks.

• Increase Caloric Intake: Pancreatic cancer treatments such as chemotherapy and radiation therapy can have side effects that affect appetite, digestion, and nutrient absorption. Weight loss can weaken the body and hinder the treatment process. 

Adequate calorie intake ensures that the body has enough energy to support various physiological processes, such as healing, recovery, and combating the side effects of treatments. Increasing caloric intake can help counteract weight loss and prevent malnutrition.

• Opt for Lean Proteins: Pancreatic cancer treatments can contribute to muscle wasting and weight loss, which can lead to weakness and decreased overall functional capacity. Lean proteins are essential for the immune system, maintenance, and repair of muscles and tissues.

When selecting lean proteins, aim for options such as skinless poultry, fish, eggs, legumes (beans, lentils, chickpeas), and tofu. These options are lower in fat and can be easily incorporated into a well-balanced diet.

• Emphasize Plant-Based Foods: A plant-based diet rich in fruits, vegetables, and whole grains has been associated with numerous health benefits. Including a variety of colorful fruits and vegetables in your meals can provide essential vitamins, minerals, antioxidants, and fiber that support your immune system and overall health.

Aim to have a rainbow of colors on your plate, as different colored fruits and vegetables offer unique nutrients and health-promoting compounds. Incorporate whole grains like quinoa, brown rice, and whole wheat bread, which are high in fiber and provide sustained energy.

• Stay Hydrated: Proper hydration is essential for everyone, especially individuals dealing with pancreatic cancer. It is important to drink plenty of fluids throughout the day to prevent dehydration, maintain electrolyte balance, and support bodily functions.

Water is the best choice, but you can also include herbal teas, clear broths, and low-sugar beverages. Avoid excessive consumption of caffeine and alcohol, as they can contribute to dehydration. If you have difficulty drinking large amounts at once, try sipping fluids slowly throughout the day or setting reminders to ensure you are staying adequately hydrated.

• Manage Fat Intake: While some fats are beneficial, others can be harmful, especially if you have pancreatic cancer. It is important to manage your fat intake to support overall health and digestion.

Limit your consumption of saturated fats found in red meat, fried foods, and full-fat dairy products. These fats can be difficult to digest and may contribute to gastrointestinal symptoms. Instead, choose healthier fats, such as those found in nuts, seeds, avocados, and fatty fish like salmon. These sources of healthy fats provide essential nutrients and can support brain function, cardiovascular health, and overall well-being.

• Control Sugar Intake: Pancreatic cancer can affect your body’s ability to regulate blood sugar levels, making it important to control your sugar intake.

Minimize your consumption of sugary foods and beverages, including sweets, sodas, and processed snacks. These sugary items can cause blood sugar spikes and contribute to inflammation and poor overall health. Instead, opt for natural sweeteners found in fruits and use them to satisfy your sweet tooth. Fruits not only provide natural sugars but also come with essential nutrients, fiber, and antioxidants that support your immune system.

• Modify Cooking Techniques: Certain cooking methods can make your meals easier to digest, reducing the risk of discomfort and digestive issues. Consider steaming, baking, grilling, or poaching foods rather than frying or using excessive oil. These techniques help retain nutrients while reducing the intake of unhealthy fats.

Experiment with different seasonings and herbs to enhance the flavor of your meals without relying heavily on salt, which can lead to fluid retention. Adjusting your cooking techniques can make your meals more enjoyable and help you maintain good nutrition during pancreatic cancer treatment.

• Seek Professional Guidance: Every individual’s journey with pancreatic cancer is unique, and it’s important to consult a registered dietitian or nutritionist specializing in oncology to develop a personalized meal plan that suits your specific needs and dietary restrictions. They can provide valuable advice on nutrition, supplementation, and managing side effects.

A professional can help you address any concerns you may have and create a plan tailored to your individual circumstances. They can also monitor your progress and make necessary adjustments to your diet as your treatment progresses, ensuring you continue to maintain good nutrition throughout your journey.

Maintaining good nutrition is vital for individuals living with pancreatic cancer. By following these ten diet tips, you can support your body’s nutritional needs, manage symptoms, and enhance your overall well-being. Remember, it’s essential to consult with a healthcare professional to receive personalized advice based on your unique circumstances. They can help you navigate any challenges you may face and provide guidance on managing side effects, incorporating supplements if necessary, and creating a sustainable and enjoyable diet plan. Stay strong, focus on a balanced diet, and take care of yourself during this challenging time.

Did you know that more than 95% of pancreatic cancers are classified as exocrine tumors? These tumors start in the exocrine cells, which make pancreatic enzymes that help in digestion. Within this category, the vast majority of tumors are adenocarcinomas.

Access to early detection screening and genetic testing is crucial! Learn how even a small donation can make a BIG impact. Join us in our mission to advance the early detection of pancreatic cancer to transform the landscape of this disease and improve survival rates. 

Help Us Put An End To Pancreatic Cancer

At TrovaNOW, our mission is to raise funding for collaborative research focused on the early detection of pancreatic cancer. Together, we can support the PRECEDE Consortium and make a difference in the fight against this devastating disease. 

Our ultimate goal is to increase the 5-year survival rate from 12% to 50% within the next 10 years. 

Visit our website at www.trovanow.com to learn more about how you can get involved and help us make a significant impact in the battle against pancreatic cancer.

The pancreas plays an incredibly important role in overall health, aiding with digestion and regulation of the amount of sugar in your bloodstream. Unfortunately, cancer is the second leading cause of death among men and women in the United States. Within that, pancreatic cancer is the third-leading cause of cancer deaths and the number of people diagnosed with it is on the rise every year. 

Pancreatic cancer remains one of the most challenging and devastating diseases, with low survival rates and limited treatment options. Pancreatic cancer rarely causes symptoms until it’s quite advanced, so most people have widespread disease at the time they’re diagnosed. The pancreas is deep inside the middle of the body, so early tumors can’t be seen or felt by healthcare providers during routine physical exams.

Sadly, pancreatic cancer still has one of the lowest 5-year survival rates of any kind of cancer, at about 12%. It’s time to dramatically improve that number. Every day, more than 1,257 people WORLDWIDE are diagnosed with pancreatic cancer. An unacceptably high proportion of these cases are diagnosed at stage 3 or 4. Early detection is the key to improving patient outcomes. 

TrovaNow is an organization that raises funds to support the Pancreatic Cancer Early Detection (PRECEDE) Consortium. PRECEDE’s mission is to transform the outcome and survival rates of pancreatic cancer through early detection. Our goal is to increase the 5-year survival rate from 12% to 50% within the next 10 years. Here’s what you need to know!

• The Importance of Early Detection and Prevention: Investing in early detection is essential in battling pancreatic cancer. Detecting the disease in its beginning stages greatly increases the likelihood of timely treatment and better patient outcomes.

TrovaNow understands the importance of early detection and prevention and utilizes its resources to support research programs that target early identification. The ultimate goal of TrovaNow’s efforts is to reduce the impact of pancreatic cancer on patients and improve their overall quality of life.

• TrovaNow: Advancing Early Detection Research: TrovaNow has positioned itself at the forefront of the battle against pancreatic cancer through its unwavering commitment to early detection through its support of the PRECEDE Consortium. PRECEDE is a groundbreaking research collaboration focused on improving early detection methods for pancreatic cancer.

TrovaNow supports the exploration and development of cutting-edge technologies, advanced imaging techniques, and novel biomarkers and liquid biopsies to identify pancreatic cancer at its earliest and most treatable stages. By investing in these innovative approaches, TrovaNow is driving the progress of early detection research and paving the way for improved patient outcomes.

• Collaborations and Partnerships: To accelerate advancements in early detection research, TrovaNow has formed strategic partnerships with leading research institutions and garnered support from medical professionals and experts in the field. By fostering collaborations, TrovaNow enables the exchange of knowledge, resources, and expertise, creating synergistic efforts.

These partnerships empower researchers to pool their strengths, leverage state-of-the-art technologies, and conduct large-scale studies to make significant strides in identifying pancreatic cancer earlier. Through these collaborations, TrovaNow amplifies the impact of research efforts and fosters an environment of collective expertise focused on the early detection of pancreatic cancer.

• TrovaNow’s Vision: Increasing 5-Year Survival Rates: TrovaNow’s ultimate goal is to increase the 5-year survival rate for pancreatic cancer from the current 12% to an ambitious 50% within the next 10 years. This vision drives their dedication to funding early detection research. By detecting the disease at an earlier stage, patients can receive timely interventions, leading to improved treatment options and increased survival rates.

TrovaNow’s commitment to this vision instills hope for a future where pancreatic cancer is no longer a devastating diagnosis. By investing in research initiatives focused on early detection, TrovaNow is paving the way for significant improvements in patient outcomes and transforming the landscape of pancreatic cancer.

• Success Stories and Promising Results: TrovaNow’s support has already yielded promising results. Through collaborative research efforts, they have witnessed success stories of early detection leading to improved patient outcomes. Innovative screening tools, advanced imaging techniques, and the exploration of biomarkers have all contributed to identifying pancreatic cancer in its early stages, increasing the chances of successful treatment. These success stories provide inspiration and hope for both patients and medical professionals.

Patient testimonials serve as a testament to the positive impact TrovaNow’s research support has made in their lives, underscoring the significance of early detection in improving prognosis and survival rates for pancreatic cancer.

• Challenges and Future Directions: While TrovaNow has made significant strides in advancing early detection research, challenges remain. Pancreatic cancer’s elusive nature and lack of easily detectable symptoms pose hurdles in identifying the disease at its earliest stages. However, TrovaNow remains steadfast in its commitment to overcoming these challenges. They aim to expand research efforts, foster additional collaborations, and explore emerging technologies to refine early detection methods. By addressing these challenges head-on, TrovaNow aims to further enhance the accuracy and effectiveness of early detection strategies for pancreatic cancer. Continued support and funding are crucial to sustaining these research initiatives and paving the way for further breakthroughs.

TrovaNow’s vision and impact on pancreatic cancer research, specifically in the realm of early detection, cannot be overstated. By raising funds and supporting collaborative research efforts, TrovaNow is pushing the boundaries of knowledge and innovation in the field. With a goal of increasing the 5-year survival rate for pancreatic cancer, TrovaNow is leading the charge toward earlier detection, better treatment options, and improved patient outcomes. Through their unwavering commitment, we can look forward to a future where pancreatic cancer is diagnosed early, enabling more lives to be saved.

Every year, National Cancer Survivor Month is celebrated in June. This month recognizes and celebrates the millions of people who have bravely and successfully battled cancer.

We encourage you to check in, offer support and share resources to those coping with life as a cancer survivor.

Giving is not just about making a donation, it’s about making a difference.​​​​​​​​ Join us in our mission and donate today to advance the early detection of pancreatic cancer and save lives. Visit www.trovanow.com to learn how you can get involved and donate today.

Pancreatic cancer rarely causes symptoms until it’s quite advanced, so most people have widespread disease at the time they’re diagnosed. Only about 1 in 5 have a tumor that can be surgically removed. Even among that subset, pancreatic cancer rebounds 75% of the time.

There is no guaranteed way to prevent pancreatic cancer, but adopting a healthy lifestyle can help reduce the risk. Here are some tips to promote overall wellness:

• Maintain a Balanced Diet – High consumption of sugary drinks, fats, red and processed meats may increase the risk of developing pancreatic cancer.

About 20% of obese people have an increased risk of developing pancreatic cancer. The risk is even higher in people who have been obese since childhood. 

Eating healthy and maintaining a healthy weight may help lower your risk for pancreatic cancer. A balanced diet that includes a variety of fruits and vegetables, choose whole grains over processed grains, limit or avoid your intake of red and processed meats, alcohol consumption, and reduce your intake of sugary and high-fat foods.

• Stay Physically Active – Make physical activity a regular part of your daily routine. Aim for at least 30 minutes of physical activity per day.

Regular exercise has many benefits for those with pancreatic cancer. Exercise can improve mood, energy levels, and overall physical health. Types of exercise recommended include walking, swimming, and yoga. Gradually incorporating exercise into a daily routine can help to build strength and endurance.

• Quit Smoking – Smoking is a known risk factor for pancreatic cancer. People who smoke are two times more likely to develop pancreatic cancer compared to those who have never smoked before. About  20-35% of pancreatic cancers are caused by cigarette smoking. 

Quitting smoking can have many benefits, including reducing the risk of cancer recurrence. Strategies to quit smoking include nicotine replacement therapy, counseling, and support groups.

• Manage Stress – Stress can have a negative impact on cancer treatment.

Techniques for stress management such as meditation, deep breathing, and yoga can help to reduce stress and improve overall well-being.

• Get Regular Check-Ups – Regular follow-up appointments are important for those with pancreatic cancer. Monitoring for recurrence is essential for early detection and treatment. Support resources for cancer survivors can provide emotional support and information about treatment options.

Did you know Pancreatic cancer is expected to be the 2nd leading cause of cancer-related deaths in the U.S. by 2030? We want to change that. 

We encourage you to join us in supporting pancreatic cancer patients and their families through early detection and prevention.⁣ We stand with all people and their families who are affected by pancreatic cancer. 

Who will benefit from the funds we raise for the PRECEDE Consortium? ⁣

By donating to TrovaNOW, you can help PRECEDE Consortium determine who is at elevated risk for pancreatic cancer, better define that risk, and enroll those at elevated risk into state-of-the-art screening programs. With this large-scale cohort, we hope these studies will also lead to the validation of an early detection blood test and prevention clinical trials in the future.⁣

At TrovaNOW, our mission is to raise funding for collaborative research for early detection and prevention – with the aim of increasing the 5-year survival rate from 12% to 50% within the next 10 years.

Visit www.trovanow.com to learn how you can get involved and donate today.

Patient education in pancreatic cancer is very important because it helps the patient and their family understand the available treatment options, the side effects of the treatment, nutrition support during the treatment and lastly, know when to seek medical attention.

• Understanding the treatment options available – There are different treatments for patients with pancreatic cancer, depending on several factors including the size and location of the tumor, type, stage and overall health of the patient. Treatment options include: 

• • Surgery
  • Chemotherapy
  • Radiation Therapy
  • Chemoradiation Therapy
  • Targeted Therapy
  • Immunotherapy

• Understanding the side effects of treatment –  Educating patients will help them manage the potential side effects of their treatment. Here are the common side effects of pancreatic cancer treatment. The patient may experience:

• • Pain
  • Fatigue
  • Nausea and Vomiting
  • Changes in Stool
• Importance of nutritional support during treatment – Healthy lifestyle is always the first step to overall wellness. Eating healthy and maintaining a healthy weight may help lower your risk. The American Cancer Society recommends following a balanced diet that includes plenty of fruits, vegetables, whole grains, and that limits or avoids processed meats, sugary drinks, and highly processed foods.
• Knowing when to seek medical attention – One of the reasons pancreatic cancer is so difficult to detect early is because many of these symptoms are more likely to be caused by other conditions or there are no symptoms at all. Patients should be informed about the signs and symptoms and who to contact in case of an emergency. Check with your doctor if you have any of the symptoms. Some common symptoms of pancreatic cancer include:

• • Belly or back pain
  • Weight loss 
  • Poor appetite
  • Nausea and vomiting
  • Diabetes

Benefits of Patient Education in Pancreatic Cancer Care

If the patient and their family are well informed about everything they need to know like about the disease, treatment options, how to manage symptoms and potential side effects, then patients are more likely to stick to their treatment plan, medications and follow up appointments. The benefits of patient education in pancreatic cancer include:

• Improved patient outcomes 
• Better adherence to treatment plans
• Enhanced quality of life
• Improved emotional well-being

Strategies for Effective Patient Education in Pancreatic Cancer Care

• Clear communication between patient and healthcare provider – What is the importance of good communication between patients and healthcare providers? LACK of communication puts the patient safety at risk. Always remember that good communication will improve patient outcomes. Healthcare providers should take the time to explain what the patient needs to know. 
• Provision of written materials – Written materials like brochures and pamphlets are also a valuable tool that will help the patient and their family. It is used to disseminate strategies and raise health knowledge. 
• Use of multimedia resources – Multimedia can also help in patient education. Multimedia learning includes learning through the use of videos, images, animations and interactive resources online which may help better understand and support information processing.
• Involvement of support groups – Several studies have shown that joining a support group can have positive effects on both the quality of life and the survival rates of patients with pancreatic cancer. Joining support groups, online communities, local events and counseling are some ways to connect with others affected by pancreatic cancer.

With your help, together WE CAN MAKE A CHANGE in the early detection and treatment of pancreatic cancer and pancreatic cancer prevention.

TrovaNow is raising funds for PRECEDE – an international, multi-institutional collaborative consortium of world-renowned experts in pancreatic cancer.

Visit www.trovanow.com to learn how you can get involved and donate today. 

Pancreatic cancer is a challenging disease to treat, and the prognosis for patients is often poor. However, recent developments in technology and treatment have shown promise in improving patient outcomes.

Innovations in Pancreatic Cancer Treatment

Clinical Trials 

• Patients with pancreatic cancer are HIGHLY encouraged to participate in clinical trials. 
• Patients at risk of developing pancreatic cancer are encouraged to participate in studies like those being conducted by the PRECEDE Consortium to find the cancer at its earliest, most treatable stage.
• Participating in clinical trials has been shown to improve outcomes for pancreatic cancer patients.
• By participating in clinical trials, patients would be closely monitored and have access to the newest treatment and screening tests, which can help that patient potentially achieve a better outcome.
• Clinical trials can lead to improved options available for the future treatment of pancreatic cancer.

Minimally invasive surgery 

• Pancreatic tumors can be removed through robotic and laparoscopic surgery, which has the advantages of shorter recovery times and better results.
  • Laparoscopic Surgery – To remove the tumor using this method, several small abdominal incisions are made, and a laparoscope—a long, thin tube with a camera and surgical tools attached—is inserted. Compared to open surgery, laparoscopic surgery has a number of advantages, such as:
    • Fewer scars and smaller incisions
    • Reduced loss of blood
    • Faster times of recovery
    • Lower possibility of complications
  • Robotic Surgery – It uses robotic arms to perform the surgery. This technique offers several advantages , including:
    • Increased precision and control
    • Improved visualization of the surgical site
    • Reduced tremors and hand fatigue for the surgeon

As of now, surgery offers the best chance of treating pancreatic cancer. But, most patients are diagnosed at later stages and are not eligible for surgery. Developing early detection tools and tests for pancreatic cancer are urgently needed.

Nanoparticle Technology

• The NoCanTher project has developed a new technology that combines the injection of nanoparticles into the cancer with the application of hyperthermia to locally advanced pancreatic tumors.
• The technology aims to improve the effectiveness of chemotherapy and reduce side effects.

Nanofluidic Drug-Eluting Seed

• Researchers from Houston Methodist have developed a nanofluidic drug-eluting seed (NDES) that can deliver immunotherapy directly into a pancreatic tumor.
• The implantable device delivers CD40 monoclonal antibodies at a sustained low-dose.
• Ongoing studies will determine the safety and efficacy of the NDES in treating pancreatic cancer.
• The researchers hope to make this technology available as a treatment option for patients within the next five years.

The development of new technologies and treatments provides hope for improving the outcomes of pancreatic cancer patients. Clinical trials and innovative approaches like nanoparticle technology and the nanofluidic drug-eluting seed offer promising options for the future.

These treatments are still being studied, and not all patients may be eligible for them. With your donation, we can change the world. Giving is not just about making a donation, it’s about making a difference.​​​​​​​​ 

TrovaNOW is raising funds for PRECEDE – an international, multi-institutional collaborative consortium of world-renowned experts in pancreatic cancer.

At TrovaNOW, our mission is to increase pancreatic cancer survival rates through research, early detection, and prevention strategies.

With your help and donations, our research and data sharing can change the outcomes for patients diagnosed with pancreatic cancer.

Visit www.trovanow.org to learn how you can get involved and donate today.

Receiving a diagnosis of pancreatic cancer is a devastating experience for both the patient and their loved ones. A pancreatic cancer diagnosis is life-changing, which may cause patients to feel grief over the loss of their normal routine, or days when they were in better health. 

It’s important to provide emotional and physical support to help your loved one, especially through this difficult time. Here are some ways you can support a loved one diagnosed with pancreatic cancer:

• Talk openly with your support system –  Supporting a loved one with pancreatic cancer involves being present. It’s important to have someone to talk to and provide a shoulder to cry on when they need it. Let them know that you are there for them and that they are not alone, whether that’s friends, family members, a support group, or a therapist.
• Let your support system help – Pancreatic cancer can make daily tasks challenging. It’s important to remember that everyone needs help sometimes. Let your support system know specifically what kind of help you need. This can help them rest and focus on their treatment.
• Connect with others who have “been there” – Remember that everyone’s experience with pancreatic cancer is unique, but connecting with others can help you feel less alone and more empowered to cope with the challenges ahead. Joining support groups, online communities, local events and counseling are some ways to connect with others affected by pancreatic cancer.
• Learn about pancreatic cancer to feel more in control – Learning about pancreatic cancer can help patients and their loved ones feel more in control and better prepared to cope with the challenges of the disease. Don’t be afraid to ask questions about your diagnosis, treatment options, or any concerns you may have. Here are some good questions to ask:
  • What treatment(s) do you recommend? Why?
  • Are there any clinical trials available to me locally?
  • Do you provide molecular profiling to help determine additional treatment options?
  • Do you provide genetic testing to help determine treatment options?
  • What are the potential benefits and risks of each of my treatment options?
  • What blood tests, scans or other tests will I need during my treatment?  How often?
  • What are the possible side effects of my treatment options?  How likely are they to occur and can they be managed?
  • How can I expect to feel during the treatment?
• Try to maintain your normal routine – Maintaining a normal routine can be beneficial for both patients and their loved ones when coping with pancreatic cancer. Make time for activities that help you relax and reduce stress, such as exercise, meditation, or spending time in nature.
• Express or release your feelings – Expressing or releasing your feelings is an important aspect of coping with pancreatic cancer. It can be a helpful way to release tension and reduce stress.

Help us put an end to Pancreatic Cancer.

At TrovaNOW — as a non-profit raising funds for the PRECEDE Consortium – a group of worldwide expert clinicians, researchers, patients, biopharmaceutical and technology companies, we are dedicated to detecting pancreatic cancer at its earliest, most treatable stage.

The Pancreatic Cancer Early Detection (PRECEDE) Consortium was featured in Let’s Win, discussing our goal of increasing the five-year survival rate to 50 percent within the next 10 years.

Working with a multi-institutional collaborative group of experts, our specific goals are:

• To maximize the identification of high-risk individuals and to advance early detection research and clinical care.
• To develop and validate an early detection blood or other test for pancreatic cancer.
• To understand pancreatic cancer risk, including discovering pancreatic cancer susceptibility genes.
• To formulate and execute a strategic plan for pancreatic cancer prevention.

Be a hero by donating today to pancreatic cancer research, which enables the investigation of new directions for treatment options.  

Research and innovation are critical for creating breakthroughs that will improve the lives of pancreatic cancer patients.

Visit www.trovanow.com to learn how you can get involved and donate today.

Did you know that 1 in 3 people will be diagnosed with cancer in their lifetime? And 1 in 64 people could be diagnosed with pancreatic cancer. As of now, surgery offers the best chance of treating pancreatic cancer. But, most patients are diagnosed at later stages and are not eligible for surgery. 

Unlike breast cancer and colon cancer, most people are not being screened for pancreatic cancer. That is why it is so important to know the symptoms, determine if you are at elevated risk, and keep up with annual medical checkups. Some common symptoms of pancreatic cancer include belly or back pain, weight loss and poor appetite, nausea and vomiting, and diabetes. Developing more readily available, non-invasive early detection tools and tests for pancreatic cancer are urgently needed. 

Who Needs Pancreatic Cancer Screening?

People who are at high risk of developing pancreatic cancer due to factors including family history, genetic mutations, or chronic pancreatitis are often advised to get screening tests. 

While screening and diagnostic tests for pancreatic cancer are available, many people are not part of an ongoing screening program even though they may be at higher risk than the general population.  While we do not know all the risk factors, the following are some that have already been identified:

• High-risk individuals

• • Family History – People with a family history may have an increased risk of pancreatic cancer or Familial pancreatic cancer (FPC), if they have a first-degree relative (A parent, sibling, or child) who has the disease. Typically, about 10% of pancreatic cancers are considered familial or hereditary. Most cases of pancreatic cancer occur randomly or can be caused by factors such as smoking, obesity, and age.
  • Genetic Mutations – Certain genetic factors may increase the risk for pancreatic cancer, including: BRCA2, BRCA1 Mutation, and HNPCC (Hereditary Non-Polyposic Colorectal Cancer) Lynch Syndrome.
  • Chronic Pancreatitis – People with chronic inflammation of the pancreas are at increased risk of developing pancreatic cancer.

• General population – People who are experiencing symptoms such as:
• • Unexplained weight loss
  • Digestive problems
  • Abdominal pain
  • Jaundice

What Is Involved In Pancreatic Cancer Screening?

Blood and imaging tests are frequently used for pancreatic cancer screening. Depending on a person’s medical history, symptoms, and risk factors, the individual screening test may change.

• Imaging Tests
  • Endoscopic Ultrasound (EUS) – Involves passing a thin tube through the mouth into the stomach to create images of the pancreas and surrounding organs
  • Computed Tomography (CT) Scans  – Take a series of X-rays that create a 3D view of the pancreas and surrounding organs taken from different angles.
  • Magnetic Resonance Imaging (MRI) – It uses a strong magnetic field and radiofrequency waves. 
• Blood Tests – The doctor may take blood samples to check:
  • Carbohydrate antigen 19-9 (CA19-9) – It is a tumor marker. Elevated levels of this may indicate cancer.
  • Carcinoembryonic antigen (CEA) – Another blood test that could be used to check for pancreatic cancer is the CEA test. Although elevated CEA levels, like the CA 19-9 test, can be a sign of cancer, they are not always accurate. It s not used as often as CA 19-9.

How To Donate To Cancer Research?

Access to early detection screening and genetic testing is crucial! TrovaNOW is raising funds for PRECEDE – an international, multi-institutional collaborative consortium of world-renowned experts in pancreatic cancer who are dedicated to increasing early detection and pancreatic cancer survival rates. 

If you have any questions or If you want more information about how to donate to cancer research, just email us at trovanow@gmail.com or learn more at http://trovanow.com

The pancreas is a gland that is part of the digestive system. It is crucial for the absorption of vitamins and nutrients which support the liver, kidneys, nervous system, and cardiovascular system. It plays an incredibly important role in overall health and we need more research to better understand it.

Do Clinical Trials Help With Pancreatic Cancer? 

Every treatment available for pancreatic cancer today was approved through a clinical trial. These trials not only lead to the improvement of future treatments but also contribute to the advancement of medical knowledge.

• Pancreatic Cancer Treatment Challenges 

1 in every 13 cancer deaths in the U.S. is a pancreatic cancer death and about 70% of patients die within 1 year of diagnosis. Pancreatic cancer is hard to diagnose. 3 in 5 people are diagnosed at an advanced stage since it takes time to present any symptoms and is often untreatable once detected.  

As of now, surgery offers the best chance of treating pancreatic cancer. However, cancer cells have a tendency to spread quickly, making surgical removal of all cancer cells difficult. Most patients are diagnosed at later stages and are not eligible for surgery. 

• Limitations Of Current Treatments

Pancreatic cancer is one of the deadliest types of cancer to treat. The current standard treatment for pancreatic cancer includes surgery, radiation therapy, and chemotherapy. However, these treatments have limitations.

• Importance Of Clinical Trials In Developing New Treatments

The development of revolutionary pancreatic cancer treatments relies on clinical trials. Clinical trials are vital for the discovery of novel therapies that may one day treat pancreatic cancer.

They give the patient the opportunity to receive new treatments which may be more efficient than the ones they are now receiving. Patients that actually participate in clinical trials also advance medical research and help create new treatments for patients in the future. 

It is strongly advised for individuals with pancreatic cancer to take part in clinical trials and for those at elevated risk to be screened. Screening is the gateway to ensuring that you are doing everything possible to mitigate your risk and will also help patients to access clinical trials.  Through their involvement in these trials, patients can receive careful observation and potentially access the latest early detection methods and treatments, which could result in improved outcomes.

How To Donate To Cancer Research?

There is no simple screening test or other early detection tools for the disease, and its earliest symptoms are non-specific.

Developing early detection tools and tests for pancreatic cancer are urgently needed. Our life-saving studies and research programs will”

1) Improve early detection.

2) Screening.

3) Risk modeling. 

4) Early, successful treatment for those with a heritable risk for pancreatic cancer.⁣

With your help and donations, our research and data sharing can change the outcomes for patients diagnosed with pancreatic cancer. Giving is not just about making a donation, it’s about making a difference.

At TrovaNOW, our mission is to raise funding for collaborative research for early detection and prevention – with the aim of increasing the 5-year survival rate from 12% to 50% within the next 10 years.

If you have any questions or want more information just email us at trovanow@gmail.com or visit http://trovanow.com to learn how you can get involved and donate today.

In 1999, the 5-year survival rate for pancreatic cancer was just 4%. In 2023, the survival rate has tripled to 12%. Although pancreatic cancer research has advanced significantly in recent years, much more needs to be done.

Current State Of Pancreatic Cancer Research

The following are some active research areas:

• Genetics: Understanding the genetic abnormalities that contribute to the occurrence of pancreatic cancer will help researchers better understand its genetics.
• Creating Novel Medicines: Chemotherapy medications, immunotherapy, and targeted therapies are among the new pancreatic cancer treatments being created by researchers. Clinical trials for a few promising novel therapies are currently ongoing.
• Improving Early Detection: Researchers are exploring new methods for detecting pancreatic cancer in its early stages, including blood tests, imaging tests, and genetic testing.

The Importance Of Early Detection In Pancreatic Cancer

What makes pancreatic cancer cells unique? Not only do pancreatic cancer cells grow unusually fast, but they can also break off from the tumor early in the disease and spread. We know that scar tissue tends to form around the tumor, which may serve as a barrier to therapeutic agents.

There’s a complex interplay between the tumor and its environment which further protects the tumor from chemotherapy and radiation and helps it evade the immune system.

Pancreatic cancer does not discriminate. It is sometimes called a “silent cancer” since it takes time to present any symptoms and is often untreatable once detected. 

The Impact Of Donations On Early Detection Pancreatic Cancer Research

Despite the progress being made, funding for pancreatic cancer research is still relatively low compared to other cancers. Pancreatic Cancer is the deadliest common cancer, yet it receives less than 3% of cancer research funding. 

There have been several successful research projects funded by donations that have contributed to our understanding of pancreatic cancer and improved patient outcomes.

Earlier detection can save lives. Pancreatic cancer is most treatable in its early stages. Earlier detection means more patients could be eligible for surgery to remove their tumors, which could lead to significantly higher survival rates.

The gift of health can change the world. Your donations WILL help save lives. Donate Today!

Without early diagnosis and intervention, most patients are diagnosed when their cancer has progressed to a late stage, leaving patients and their loved ones feeling hopeless.  

At TrovaNOW, our mission is to increase pancreatic cancer survival rates through research, early detection, and prevention strategies. 

Research and innovation are critical for creating breakthroughs that will improve the lives of pancreatic cancer patients.

What could the future of early detection for pancreatic cancer look like?  We are working to find a way to detect this deadly cancer at its earliest stages, either through a blood test or other means, so that the cancer can be removed and stopped in its tracks.  

We encourage you to join us in supporting pancreatic cancer patients and their families through early detection and prevention.⁣ We are not powerless against pancreatic cancer. We are fighting the fight while finding the cure – but we can’t do it alone. 

If you have any questions or If you want more information just email us at trovanow@gmail.com or visit http://trovanow.com to learn how you can get involved and donate today.