Early Cancer Detection: Who Should Consider Pancreatic Cancer Screening?

August 7, 2023

Precede Foundation

Pancreatic cancer is a highly aggressive and often asymptomatic disease, making early detection challenging. The five-year survival rate for pancreatic cancer is dismally low, mainly because the majority of cases are diagnosed at advanced stages when treatment options are limited. However, with advancements in medical technology and research, pancreatic cancer screening has emerged as a potential tool for early detection and improved outcomes. In this blog post, we will explore who should consider pancreatic cancer screening and the importance of early detection.

Pancreatic Cancer: Risk Factors and Symptoms

Understanding the risk factors associated with pancreatic cancer is crucial in identifying individuals who might benefit from screening. Age is a significant risk factor, with the overwhelming majority of cases occurring in individuals over the age of 45. Some controllable risk factors may also increase your chance of a pancreatic cancer diagnosis including smoking and obesity. Other risk factors include chronic pancreatitis and a family history of pancreatic cancer. Recognizing the early symptoms of pancreatic cancer, such as abdominal pain, unexplained weight loss, and jaundice, can prompt individuals to seek early screening.

Current Screening Guidelines for Pancreatic Cancer

Several organizations have established screening guidelines for pancreatic cancer. These guidelines typically recommend screening for individuals who are at high risk of developing pancreatic cancer. Individuals with a family history, genetic mutations and chronic pancreatitis are often advised to get screening tests. Many people are not part of an ongoing screening program even though they may be at higher risk than the general population. The current screening methods are limited and research is ongoing to develop more accurate and accessible techniques.

High-Risk Groups: Who Should Consider Pancreatic Cancer Screening?

Individuals with a strong familial history of pancreatic cancer should be considered for screening if two or more first-degree relatives have been affected. Additionally, those with hereditary conditions like BRCA1, BRCA2, or Lynch syndrome may also be at an elevated risk and should be evaluated for early screening. Moreover, individuals who have undergone treatment for chronic pancreatitis or diabetes are potential candidates for screening due to the increased risk of developing pancreatic cancer associated with these conditions.

Available Screening Techniques for Pancreatic Cancer

Various screening methods are employed to detect pancreatic cancer at an early stage. Imaging tests, including computed tomography (CT) scans, magnetic resonance imaging (MRI), and endoscopic ultrasound (EUS), are commonly used to visualize the pancreas and surrounding tissues for any abnormalities. Additionally, biomarker tests, such as measuring levels of CA19-9 and CEA in the blood, can provide valuable information in conjunction with imaging tests. Genetic testing is also essential in identifying hereditary pancreatic cancer risk, enabling personalized screening recommendations.

Benefits and Limitations of Pancreatic Cancer Screening

Early detection through screening offers several potential benefits, such as increased treatment options and improved survival rates. Identifying pancreatic cancer at an early stage allows for more effective surgical interventions, targeted therapies, and a better chance of achieving a cure. Moreover, early detection can lead to better palliative care and improved quality of life for patients.

However, pancreatic cancer screening also has limitations, including false-positive results that may cause anxiety and unnecessary follow-up procedures. Additionally, the sensitivity and specificity of current screening methods need improvement to ensure accurate and reliable results. As a result, screening should be approached with caution, and decisions should be made in consultation with healthcare professionals.

The Role of Genetic Counseling and Testing

Genetic counseling plays a vital role in guiding individuals at high risk of pancreatic cancer to make informed decisions about screening. A genetic counselor can assess an individual’s family history and recommend appropriate genetic testing to identify any hereditary factors. Understanding the genetic basis of pancreatic cancer risk empowers individuals to take proactive steps towards early detection and risk reduction.

Genetic testing can provide essential information about an individual’s predisposition to pancreatic cancer, helping to tailor personalized screening plans and preventive measures. For individuals with identified genetic mutations linked to pancreatic cancer, increased surveillance and close monitoring may be recommended.

Early Detection and Beyond: Importance of Lifestyle and Risk Reduction

While screening is a valuable tool, it is essential to emphasize the role of lifestyle modifications in reducing pancreatic cancer risk. Adopting a healthy lifestyle can help reduce the risk of pancreatic cancer, including maintaining a healthy weight through diet and 30 minutes of exercise per day

About 20-35% of pancreatic cancers are caused by cigarette smoking. Quitting smoking is one of the most effective ways to reduce the risk of developing this deadly disease. Additionally, minimizing exposure to environmental carcinogens and managing chronic conditions, such as diabetes and pancreatitis, can contribute to risk reduction.

Pancreatic cancer remains a formidable challenge in the medical field, but early detection through screening offers hope for improved outcomes. High-risk individuals, such as those with a family history of pancreatic cancer or specific genetic mutations, should consider screening options in consultation with healthcare professionals. While screening is an essential step, promoting a healthy lifestyle and risk reduction strategies is equally crucial in the fight against pancreatic cancer. With ongoing research and advancements in medical technology, the future of pancreatic cancer screening holds promise for earlier detection and increased survival rates. By raising awareness about the importance of early detection and empowering individuals with knowledge about their risk, we can take significant steps towards reducing the burden of pancreatic cancer on individuals and communities.

Join the battle

Let’s stand together against pancreatic cancer and strive for increasing the 5-year survival rate to 50% within the next 10 years.⁣ We see big opportunities for making advances to pancreatic cancer survival rates.

Establishing a first-of-its-kind program for early detection and prevention includes a research initiative to identify biomarkers of abnormal pancreatic cells so we can intervene before they become invasive cancer cells. We’re also focusing on people who have had multiple family members with pancreatic cancer or who have mutations linked to pancreatic cancer.

The goal is to develop new treatment paradigms to markedly delay or prevent the formation of pancreatic cancer in high-risk individuals. TrovaNOW proceeds go towards collaborative research on pancreatic cancers earlier detection, saving thousands of lives from the world’s deadliest cancer.

If you have any questions or If you want more information about how to donate, just email us at trovanow@gmail.com or learn more by visiting our website www.trovanow.org

Knowing When To Ask For Help

There’s strength in recognizing when you need additional support. If you’re feeling consistently overwhelmed, anxious, or depressed, it may be time to speak with a healthcare professional. Warning signs can include ongoing sleep trouble, loss of appetite, or emotional numbness.

Mental health care is an important part of cancer recovery. There are therapists, social workers, and cancer-specific counselors trained to support your unique needs. Don’t hesitate to seek them out.

Your medical team can help adjust medications or recommend physical therapy if your symptoms are impacting your daily life. Being honest about your struggles allows your care providers to offer better, more personalized support.

The path to recovery from pancreatic cancer is rarely straightforward. It’s a mix of triumphs and setbacks, strength and vulnerability. But through each high and low, healing is happening. Be gentle with yourself. Allow space for rest, reflection, and growth.

You don’t have to go through this journey alone. With the right support, emotional, physical, and practical, you can move forward, one step at a time. And remember, every day you show up for yourself is a victory.

At TrovaNOW, we’re focused on finding a cure for pancreatic cancer. Every test and discovery brings us closer to better treatments and saving lives. Join us and learn more at TrovaNOW.

PRECEDE Foundation Inaugural Gala

Join us for a night at the Tribeca Rooftop 360 on October 28th at 3:00pm PDT to honor the following awards:

Nobility in Science Award

Raymond C. Wadlow, MD

Catalyst for Change Award

Ambry Genetics Corporation

Legacy Awards

Jeffrey Johnson, Esq.

Jonathan Morris, Esq.

PRECEDE Leadership and Compassionate Care Award

Jessica Everett, MS, CGC

Co-Chairs

Scott Berger | Michael Gershenson | Tracy Chen

Honorary Chairs

Diane Simeone, MD | Jamie Brickell

Get tickets here.

A Long and Steadfast Battle Against a Terrible Cancer

Raymond Wadlow lost his mom, Emily Couric, to pancreatic cancer in 2001. Today he’s an oncologist pushing for early detection.

Why Building Muscle Matters (Strength Training After Cancer Treatment)

Cancer treatment is an incredibly challenging journey, often leaving survivors physically and emotionally drained. While survival is the primary goal, the road to recovery requires more than just healing from the illness itself, it requires rebuilding strength and endurance. One of the most effective ways to regain strength and improve quality of life after treatment is through strength training.

In this blog, we’ll explore why building muscle matters after cancer treatment, how strength training supports recovery, and why it’s important to include physical activity in a full recovery plan.

The Importance of Muscle Health in Cancer Recovery

During cancer treatment, particularly chemotherapy and radiation, the body goes through a variety of changes, including significant muscle loss. This can lead to fatigue, weakness, and a decrease in overall functional capacity. Survivors may also experience joint pain, decreased bone density, and difficulty with mobility. When muscles are weakened, it becomes more difficult to perform everyday tasks, affecting the ability to return to normal life.

Muscle health is crucial for maintaining daily functioning, increasing stamina, and improving the body’s ability to heal. Building muscle after cancer treatment can help counteract the physical decline caused by treatments, reduce fatigue, and increase energy levels. Strong muscles are also important for stability, balance, and preventing falls or injuries, which can be especially crucial as the body regains strength.

Benefits of Strength Training After Cancer Treatment

Physical Benefits

Strength training is an excellent way to rebuild muscle mass lost during cancer treatment. By focusing on resistance exercises that challenge the muscles, you can restore strength and regain physical independence. Whether through bodyweight exercises, free weights, or resistance bands, strength training helps increase muscle mass, boost stamina, and promote flexibility.

It also improves bone density, which is particularly important for cancer survivors who may be at risk of osteoporosis due to treatments like chemotherapy and hormone therapy. As you build muscle, you reduce the risk of bone fractures and improve posture and stability.

Mental and Emotional Benefits

Physical activity, especially strength training, has significant mental health benefits. Exercise releases endorphins, which are natural mood boosters that help reduce anxiety and depression. Cancer survivors often experience feelings of helplessness and loss of control. Strength training helps you regain control over your body, build confidence, and feel accomplished.

Strength training offers mental benefits like improved mood and focus. Research shows that regular exercise can also help manage the cognitive effects of cancer treatment, such as “chemo brain,” which can cause memory issues, difficulty concentrating, and brain fog. Strength training can improve cognitive function, helping survivors feel more mentally sharp and focused.

Long-Term Health Benefits

Strength training can help prevent long-term complications of cancer treatment. Conditions such as sarcopenia (muscle wasting) and metabolic syndrome, which involves high blood pressure, high blood sugar, and abnormal cholesterol levels, are common among cancer survivors. Building muscle through strength training can help manage these conditions and reduce the risk of chronic diseases.

Muscle health supports overall immune function and metabolism. Strong muscles help regulate blood sugar levels, enhance circulation, and improve the body’s ability to absorb nutrients, critical for recovery and long-term health.

The Science Behind Strength Training for Cancer Survivors

Strength training works by creating small tears in muscle fibers, which, when repaired, become stronger over time. After cancer treatment, the body may be in a weakened state, but through consistent resistance training, it begins to rebuild muscle tissue. This process is essential for improving muscle mass and overall body strength.

Strength training promotes hormone regulation, which can be disrupted by cancer treatments. Chemotherapy and hormone therapy often interfere with estrogen and testosterone levels. Regular strength training helps balance these hormones, which can improve mood, energy levels, and general well-being.

Studies have shown that strength training can help cancer survivors reduce fatigue, improve cardiovascular health, and maintain a healthy weight. This holistic approach is vital to fully recovering from the effects of cancer treatment and returning to a normal, active lifestyle.

Key Considerations When Starting Strength Training Post-Treatment

Starting strength training after cancer treatment should be approached with care. The body may be more sensitive and vulnerable in the recovery phase, so it’s essential to consult with a healthcare provider or physical therapist before beginning an exercise program.

Start Slow and Progress Gradually: Don’t jump into intense workouts right away. Begin with low-impact exercises that focus on mobility, flexibility, and core strength. Gradually increase the intensity and duration of your workouts as your body adapts. Listen to your body, rest when needed, and avoid pushing too hard.
Focus on Recovery and Balance: Incorporating rest days into your routine is just as important as training days. Overtraining can lead to injury or burnout, so make sure you balance strength training with adequate recovery. This includes prioritizing sleep, nutrition, and hydration as part of your overall fitness plan.
Adapt Exercises to Your Body’s Needs: Cancer treatment can result in lingering side effects like joint pain, fatigue, and reduced range of motion. Modify exercises to accommodate these challenges. Resistance bands and light weights can be excellent starting points for those who need to ease into strength training.

Effective Strength Training Exercises for Cancer Survivors

Cancer survivors can begin their strength training journey with simple, low-impact exercises that target the major muscle groups. Here are some effective exercises to get started:

Bodyweight Squats: Squats are a great full-body exercise that targets the legs, glutes, and core. Start by performing shallow squats and gradually increase the depth as you build strength.
Wall Push-ups: Wall push-ups are an excellent way to build upper body strength without straining the shoulders or wrists. As you gain strength, progress to standard push-ups or modified knee push-ups.
Resistance Band Exercises: Resistance bands are perfect for adding gentle resistance to exercises like bicep curls, shoulder presses, and leg extensions. They provide controlled resistance that’s easier on the joints.
Dumbbell Exercises: Once you’ve built up some strength, you can incorporate light dumbbells for exercises like lunges, chest presses, and rows to continue building muscle.
Core Workouts: Strengthening your core is essential for improving balance and stability. Exercises like planks, bird dogs, and leg raises are great for building a solid foundation of strength.

Building a Strength Training Routine

Creating a strength training routine that fits your needs is essential for long-term success. Here are some tips for creating a sustainable workout plan:

Frequency: Aim for two to three strength training sessions per week, spaced out to allow for adequate recovery.
Duration: Start with 20-30 minute sessions and gradually increase the time as your body becomes more accustomed to the routine.
Progression: Increase the resistance, repetitions, or sets as you build strength. A good rule of thumb is to challenge your muscles without overexerting yourself.
Consistency: Make strength training a regular part of your life, but be patient with the process. Progress may be slow, but every step forward is a victory.

Building muscle after cancer treatment is a powerful tool in the recovery process. Strength training not only helps rebuild muscle mass and physical strength, but it also provides emotional and mental benefits that can enhance overall well-being. By embracing a thoughtful, gradual approach to strength training, cancer survivors can regain control of their bodies, improve their health, and achieve a higher quality of life. Remember, consistency is key, strength comes over time.

In 2025, TrovaNow is expanding its impact—with a 40% increase in fundraising goals and more research sites dedicated to supporting cancer recovery. Visit www.trovanow.com to see how you can get involved and donate today.